2023
Markerless head motion tracking and event-by-event correction in brain PET
Zeng T, Lu Y, Jiang W, Zheng J, Zhang J, Gravel P, Wan Q, Fontaine K, Mulnix T, Jiang Y, Yang Z, Revilla E, Naganawa M, Toyonaga T, Henry S, Zhang X, Cao T, Hu L, Carson R. Markerless head motion tracking and event-by-event correction in brain PET. Physics In Medicine And Biology 2023, 68: 245019. PMID: 37983915, PMCID: PMC10713921, DOI: 10.1088/1361-6560/ad0e37.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrainHeadHumansImage Processing, Computer-AssistedMotionMovementPhantoms, ImagingPositron-Emission TomographyConceptsPoint source studyHead motion correctionSmaller residual displacementMotion correctionIterative closest point (ICP) registration algorithmHead motion trackingSpatial resolutionResidual displacementData-driven evaluation methodHigh spatial resolutionLow noiseMotion trackingStereovision cameraMotion tracking deviceStructured lightEvent correctionBrain positron emission tomography (PET) imagingTracking deviceReconstruction resultsHMT methodPoint cloudsNegative biasReference cloudUMTEvaluation method
2017
Direct reconstruction of parametric images for brain PET with event-by-event motion correction: evaluation in two tracers across count levels
Germino M, Gallezot JD, Yan J, Carson RE. Direct reconstruction of parametric images for brain PET with event-by-event motion correction: evaluation in two tracers across count levels. Physics In Medicine And Biology 2017, 62: 5344-5364. PMID: 28504644, PMCID: PMC5783541, DOI: 10.1088/1361-6560/aa731f.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArtifactsBrainHumansImage Processing, Computer-AssistedMaleMovementPhantoms, ImagingPositron-Emission Tomography
2014
Applications of the line-of-response probability density function resolution model in PET list mode reconstruction
Jian Y, Yao R, Mulnix T, Jin X, Carson RE. Applications of the line-of-response probability density function resolution model in PET list mode reconstruction. Physics In Medicine And Biology 2014, 60: 253-278. PMID: 25490063, PMCID: PMC4820078, DOI: 10.1088/0031-9155/60/1/253.Peer-Reviewed Original ResearchEvaluation of bias and variance in low-count OSEM list mode reconstruction
Jian Y, Planeta B, Carson RE. Evaluation of bias and variance in low-count OSEM list mode reconstruction. Physics In Medicine And Biology 2014, 60: 15-29. PMID: 25479254, PMCID: PMC4823773, DOI: 10.1088/0031-9155/60/1/15.Peer-Reviewed Original Research
2012
Direct 4-D PET List Mode Parametric Reconstruction with a Novel EM Algorithm
Yan J, Planeta-Wilson B, Carson RE. Direct 4-D PET List Mode Parametric Reconstruction with a Novel EM Algorithm. IEEE Transactions On Medical Imaging 2012, 31: 2213-2223. PMID: 22929383, PMCID: PMC3660152, DOI: 10.1109/tmi.2012.2212451.Peer-Reviewed Original Research
2001
Noninvasive Estimation of the Aorta Input Function for Measurement of Tumor Blood Flow with [15O]Water
Watabe H, Channing M, Riddell C, Jousse F, Libutti S, Carrasquillo J, Bacharach S, Carson R. Noninvasive Estimation of the Aorta Input Function for Measurement of Tumor Blood Flow with [15O]Water. IEEE Transactions On Medical Imaging 2001, 20: 164-174. PMID: 11341707, DOI: 10.1109/42.918468.Peer-Reviewed Original ResearchDevice‐dependent activity estimation and decay correction of radionuclide mixtures with application to Tc‐94m PET studies
Smith M, Daube‐Witherspoon M, Plascjak P, Szajek L, Carson R, Everett J, Green S, Territo P, Balaban R, Bacharach S, Eckelman W. Device‐dependent activity estimation and decay correction of radionuclide mixtures with application to Tc‐94m PET studies. Medical Physics 2001, 28: 36-45. PMID: 11213920, DOI: 10.1118/1.1333411.Peer-Reviewed Original ResearchConceptsMo targetDecay studiesGamma-ray emissionRadionuclide mixturesHigh-purity germanium detectorTheoretical sensitivity modelPurity germanium detectorDecay correctionDose calibratorExperimental decay curvesRay emissionGermanium detectorTc isotopesMo-94Proton irradiationDecay curvesDecay-corrected activityPET scannerDecay rateBombardmentAnalytic formulaTcPositronsQuantitative PETSensitivity factors
2000
Measurement of dopamine release with continuous infusion of [11C]raclopride: optimization and signal-to-noise considerations.
Watabe H, Endres CJ, Breier A, Schmall B, Eckelman WC, Carson RE. Measurement of dopamine release with continuous infusion of [11C]raclopride: optimization and signal-to-noise considerations. Journal Of Nuclear Medicine 2000, 41: 522-30. PMID: 10716328.Peer-Reviewed Original ResearchConceptsOptimal timingAdministration of amphetamineReceptor imaging studiesHuman dataContinuous infusionDopamine releaseOptimal scan timeHealthy volunteersHuman studiesSynaptic dopamineImaging studiesPET studiesDopamine responsePercentage changeCareful assessmentStatistical significanceDeltaBPInfusionMeasurement of changesIndirect measureActivity curvesPrePatientsPerformance characteristics of the 3-D OSEM algorithm in the reconstruction of small animal PET images
Yao R, Seidel J, Johnson CA, Daube-Witherspoon ME, Green MV, Carson RE. Performance characteristics of the 3-D OSEM algorithm in the reconstruction of small animal PET images. IEEE Transactions On Medical Imaging 2000, 19: 798-804. PMID: 11055803, DOI: 10.1109/42.876305.Peer-Reviewed Original Research
1998
Noise characteristics of 3-D and 2-D PET images
Pajevic S, Daube-Witherspoon ME, Bacharach SL, Carson RE. Noise characteristics of 3-D and 2-D PET images. IEEE Transactions On Medical Imaging 1998, 17: 9-23. PMID: 9617904, DOI: 10.1109/42.668691.Peer-Reviewed Original Research