2024
Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic Opportunities
Valdez C, Sánchez-Zuno G, Bucala R, Tran T. Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic Opportunities. International Journal Of Molecular Sciences 2024, 25: 4849. PMID: 38732068, PMCID: PMC11084905, DOI: 10.3390/ijms25094849.Peer-Reviewed Original ResearchConceptsInhibition of MIFResponse to infectionNon-canonical signaling pathwaysClinical studiesCancer patientsClinical trialsInflammatory cytokinesDriving tumorigenesisClinical explorationCancer typesCancerDual inhibitionTherapeutic targetIn vivoIn vitroSignaling pathwayMIFAntitumor candidateBinding partners
1994
Identification of MIF as a new pituitary hormone and macrophage cytokine and its role in endotoxic shock
Bucala R. Identification of MIF as a new pituitary hormone and macrophage cytokine and its role in endotoxic shock. Immunology Letters 1994, 43: 23-26. PMID: 7737686, DOI: 10.1016/0165-2478(94)00152-9.Peer-Reviewed Original ResearchConceptsPituitary hormonesMacrophage migration inhibitory factorSystemic inflammatory responseMacrophage-derived cytokinesMigration inhibitory factorNovel pituitary hormoneEndotoxic shockMacrophage cytokinesInflammatory responseHost responseInhibitory factorProtein mediatorsHormoneCytokinesMIFPivotal roleEndotoxicResponse