2009
Macrophage migration inhibitory factor and multiple organ dysfunction syndrome
Yende S, Angus D, Bucala R. Macrophage migration inhibitory factor and multiple organ dysfunction syndrome. Journal Of Organ Dysfunction 2009, 5: 10-16. DOI: 10.1080/17471060802443653.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorMigration inhibitory factorSevere sepsisOrgan dysfunctionInhibitory factorMultiple organ dysfunction syndromeOrgan dysfunction syndromeInnate immune responseDysfunction syndromePoor outcomeCertain infectionsImmune responseHuman studiesSepsisDetrimental roleKey mediatorDysfunctionImportant predictorCritical roleDetrimental effectsGlucocorticoidsSyndromeInfection
1997
Macrophage migration inhibitory factor: a regulator of glucocorticoid activity with a critical role in inflammatory disease
Donnelly S, Bucala R. Macrophage migration inhibitory factor: a regulator of glucocorticoid activity with a critical role in inflammatory disease. Trends In Molecular Medicine 1997, 3: 502-507. PMID: 9430786, DOI: 10.1016/s1357-4310(97)01133-7.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorAcute respiratory distress syndromeRelease of MIFFunction of MIFEfficacy of glucocorticoidsRespiratory distress syndromeAnti-inflammatory effectsMigration inhibitory factorEffects of glucocorticoidsAnterior pituitary glandARDS pathogenesisDistress syndromeGlucocorticoid activityInflammatory diseasesT cellsFirst cytokineInflammatory sitesPituitary glandInhibitory factorGlucocorticoidsCritical rolePhysiological responsesCytokinesPathogenesisSyndrome