2019
MIF and MIF2 have distinct but synergistic roles in CIA pathogenesis
Doherty E, Tilstam P, Bucala R. MIF and MIF2 have distinct but synergistic roles in CIA pathogenesis. The Journal Of Immunology 2019, 202: 180.13-180.13. DOI: 10.4049/jimmunol.202.supp.180.13.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorRheumatoid arthritisT cellsCIA inductionCollagen-induced arthritis (CIA) mouse modelSevere erosive rheumatoid arthritisEffector memory T cellsCytokine macrophage migration inhibitory factorRelapsing autoimmune diseaseErosive rheumatoid arthritisProgressive joint destructionT cell infiltrationMemory T cellsAbstract Rheumatoid arthritisArthritis mouse modelSecondary lymphoid organsMigration inhibitory factorCIA pathogenesisHigh expression alleleJoint inflammationJoint destructionLymph nodesWT miceAutoimmune diseasesReceptor CD74
2017
Adoptive transfer of a novel MIF receptor (CD74+) expressing memory T cell subpopulation is sufficient to transfer inflammatory arthritis
Doherty E, Piecychna M, Leng L, Bucala R. Adoptive transfer of a novel MIF receptor (CD74+) expressing memory T cell subpopulation is sufficient to transfer inflammatory arthritis. The Journal Of Immunology 2017, 198: 156.3-156.3. DOI: 10.4049/jimmunol.198.supp.156.3.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorEffector memory T cellsMemory T cellsRheumatoid arthritisT cellsJoint inflammationAdoptive transferCollagen-induced arthritis (CIA) mouse modelSevere erosive rheumatoid arthritisCytokine macrophage migration inhibitory factorMemory T-cell subpopulationsAutoimmune joint inflammationImmune checkpoints CTLA4MIF receptor CD74Effector memory phenotypeErosive rheumatoid arthritisAbstract Rheumatoid arthritisArthritis mouse modelT cell subpopulationsMigration inhibitory factorT cell activationExpression of STAT4High expression alleleInflammatory arthritisMIF receptor