2019
Effects of autophagy on apoptosis of articular chondrocytes in adjuvant arthritis rats
Zhou R, Zhu F, Wu X, Song S, Chen Y, Zhu C, Dai B, Qian X, Wang K, Hu W, Chen F. Effects of autophagy on apoptosis of articular chondrocytes in adjuvant arthritis rats. Journal Of Cellular And Molecular Medicine 2019, 23: 7879-7884. PMID: 31508906, PMCID: PMC6815768, DOI: 10.1111/jcmm.14629.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisEffect of autophagyChondrocyte apoptosisAdjuvant arthritisDevelopment of RATreatment of RASystemic autoimmune diseaseAdjuvant arthritis ratsArticular chondrocyte apoptosisAutophagy activator rapamycinArticular cartilage injuryArticular chondrocytesRat articular cartilageArthritis ratsJoint deformityAutoimmune diseasesAA ratsCartilage injuryJoint functionChondrocyte autophagyAutophagy inhibitorPotential targetArthritisApoptosisRats
2016
Functions of interleukin‐34 and its emerging association with rheumatoid arthritis
Zhou R, Wu X, Xie Y, Dai B, Hu W, Ge J, Chen F. Functions of interleukin‐34 and its emerging association with rheumatoid arthritis. Immunology 2016, 149: 362-373. PMID: 27550090, PMCID: PMC5095491, DOI: 10.1111/imm.12660.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisIL-34Inflammatory arthritisAutoimmune diseasesDevelopment of RAInterleukin-34Active rheumatoid arthritisSystemic autoimmune diseaseEffective treatment optionExtra-articular lesionsNovel therapeutic strategiesMononuclear phagocyte lineage cellsSynovial inflammationTreatment optionsSpecific monoclonal antibodiesTherapeutic strategiesTherapeutic targetArthritisMonoclonal antibodiesExperimental modelLineage cellsMultiple jointsReceptor ligandsInflammationDisease