TET3-overexpressing macrophages promote endometriosis
Lv H, Liu B, Dai Y, Li F, Bellone S, Zhou Y, Mamillapalli R, Zhao D, Venkatachalapathy M, Hu Y, Carmichael G, Li D, Taylor H, Huang Y. TET3-overexpressing macrophages promote endometriosis. Journal Of Clinical Investigation 2024, 134: e181839. PMID: 39141428, PMCID: PMC11527447, DOI: 10.1172/jci181839.Peer-Reviewed Original ResearchDisease-associated macrophagesTET3 overexpressionHuman endometriosis lesionsPathophysiology of endometriosisPro-inflammatory cytokine productionChronic inflammatory diseaseReproductive age womenEndometriosis lesionsE3 ubiquitin ligasePathogenic macrophagesCytokine productionEndometriosisInflammatory diseasesTET3 knockdownEndometriosis progressionPathogenic contributorsLet-7 miRNA expressionAge womenMacrophagesMouse macrophagesTherapeutic targetUbiquitin ligaseTET3MiceDiseaseA NOVEL CHIMERIC IMMUNOCONJUGATE MOLECULE (ICON3) SUPPRESSES ENDOMETRIOSIS IN A MURINE MODEL
Garg A, Mamillapalli R, Krikun G, Habata S, Atwani R, Taylor H. A NOVEL CHIMERIC IMMUNOCONJUGATE MOLECULE (ICON3) SUPPRESSES ENDOMETRIOSIS IN A MURINE MODEL. Fertility And Sterility 2024, 122: e337-e338. DOI: 10.1016/j.fertnstert.2024.08.065.Peer-Reviewed Original ResearchTHERAPEUTIC EFFECT OF ENDOMETRIOSIS ASSOCIATED MICRO-RNAS ON HUMAN ENDOMETRIOSIS XENOTRANSPLANTS
Gawde N, Mamillapalli R, Taylor H. THERAPEUTIC EFFECT OF ENDOMETRIOSIS ASSOCIATED MICRO-RNAS ON HUMAN ENDOMETRIOSIS XENOTRANSPLANTS. Fertility And Sterility 2024, 122: e156-e157. DOI: 10.1016/j.fertnstert.2024.07.556.Peer-Reviewed Original ResearchTHE USE OF AMD3100 FOR BONE MARROW DERIVED MESENCHYMAL STEM CELLS MOBILIZATION IN THE TREATMENT OF ASHERMAN’S SYNDROME
Flores V, Delis P, Mamillapalli R, Taylor H. THE USE OF AMD3100 FOR BONE MARROW DERIVED MESENCHYMAL STEM CELLS MOBILIZATION IN THE TREATMENT OF ASHERMAN’S SYNDROME. Fertility And Sterility 2024, 122: e36-e37. DOI: 10.1016/j.fertnstert.2024.07.168.Peer-Reviewed Original ResearchIL-6 PREVENTS EXCESSIVE INVASION IN ENDOMETRIOSIS
Mamillapalli R, Han E, Cevik E, Gawde N, Thomas K, Taylor H. IL-6 PREVENTS EXCESSIVE INVASION IN ENDOMETRIOSIS. Fertility And Sterility 2024, 122: e157-e158. DOI: 10.1016/j.fertnstert.2024.07.558.Peer-Reviewed Original ResearchBone marrow mesenchymal stem cell-derived exosomes shuttle microRNAs to endometrial stromal fibroblasts that promote tissue proliferation /regeneration/ and inhibit differentiation
Bonavina G, Mamillapalli R, Krikun G, Zhou Y, Gawde N, Taylor H. Bone marrow mesenchymal stem cell-derived exosomes shuttle microRNAs to endometrial stromal fibroblasts that promote tissue proliferation /regeneration/ and inhibit differentiation. Stem Cell Research & Therapy 2024, 15: 129. PMID: 38693588, PMCID: PMC11064399, DOI: 10.1186/s13287-024-03716-1.Peer-Reviewed Original ResearchConceptsMiR-100-5pMiR-100MiR-21Transmission electron microscopyMiR-143MiR-143-3pMiR-21-5pEndometrial stromal fibroblastsStromal fibroblastsMicroRNAsExtracellular vesiclesElectron microscopyCell-free regenerative therapyNanoparticle tracking analysisMiRNAsBone marrow mesenchymal stem cell-derived exosomesBone marrow-derived stem cellsMesenchymal stem cell-derived exosomesStem cell-derived exosomesDelivery of microRNAsMarrow-derived stem cellsAssociated with several signaling pathwaysMediators of tissue repairMethodsExtracellular vesiclesUnpaired t-test