2017
Chapter 69 Patient Responses to Guanfacine in Cocaine Addiction
Milivojevic V, Sinha R, Fox H. Chapter 69 Patient Responses to Guanfacine in Cocaine Addiction. 2017, 679-688. DOI: 10.1016/b978-0-12-803750-8.00069-5.ChaptersAnxiety pathophysiologyDrugs of abuseNeural stress systemsDrug-seeking behaviorEmotional controlDrug seekingRecent research findingsChronic stress stateNegative consequencesCocaine addictionCocaine dependenceStress systemResearch findingsLong-term agentsCocaine useDrug useAbuseGuanfacineCravingSeekingStress sensitivityAddictionAbilityRobust adaptationOwn laboratory
2011
Modeling Relapse Situations in the Human Laboratory
Sinha R. Modeling Relapse Situations in the Human Laboratory. Current Topics In Behavioral Neurosciences 2011, 13: 379-402. DOI: 10.1007/978-3-642-28720-6_150.Peer-Reviewed Original ResearchHuman laboratoryAlcohol relapse riskStress-related dysregulationBrain imaging studiesNovel treatment interventionsHuman laboratory proceduresAlcohol-dependent individualsChronic relapsing illnessAlcohol seekingRelapse situationsStress processRelapse outcomesRelapse riskAlcohol relapseAlcohol useTreatment interventionsReciprocal relationshipEmpirical findingsAlcoholism riskCentral stressImaging studiesSuch dysregulationAlcohol consumptionSeekingAlcoholism
2001
How does stress increase risk of drug abuse and relapse?
Sinha R. How does stress increase risk of drug abuse and relapse? Psychopharmacology 2001, 158: 343-359. PMID: 11797055, DOI: 10.1007/s002130100917.Peer-Reviewed Original ResearchConceptsDrug abuseSubstance abuseMost major theoriesHuman laboratory studiesField of addictionDrug seekingDrug useTreatment developmentMajor theoriesAbuse altersStress exposureVulnerable individualsHuman researchAbuseAddictsEmpirical evidencePreclinical evidenceClinical observationsRelapseAnimal studiesPreclinical researchSeekingGreater understandingAddictionResearch