2023
Binge drinking is associated with higher cortisol and lower hippocampal and prefrontal gray matter volume: Prospective association with future alcohol intake
Fan S, Goldfarb E, Lacadie C, Fogelman N, Seo D, Sinha R. Binge drinking is associated with higher cortisol and lower hippocampal and prefrontal gray matter volume: Prospective association with future alcohol intake. Neurobiology Of Stress 2023, 25: 100540. PMID: 37323647, PMCID: PMC10265520, DOI: 10.1016/j.ynstr.2023.100540.Peer-Reviewed Original ResearchGray matter volumeDorsal lateral prefrontal cortexAlcohol use disorderSmaller gray matter volumeAlcohol intakePrefrontal gray matter volumeBinge drinkingFuture alcohol intakeMatter volumeBilateral dorsal lateral prefrontal cortexCortisol levelsStructural grey matter volumeHigher cortisolWhole-brain voxel-based morphometryAcute alcohol intakeLower gray matter volumeHigh-resolution structural MRIVoxel-based morphometryRegional gray matter volumePosterior parietal cortexMotor cortexSupplementary motorModerate drinkersUse disordersDrinking days
2012
Cumulative Adversity and Smaller Gray Matter Volume in Medial Prefrontal, Anterior Cingulate, and Insula Regions
Ansell EB, Rando K, Tuit K, Guarnaccia J, Sinha R. Cumulative Adversity and Smaller Gray Matter Volume in Medial Prefrontal, Anterior Cingulate, and Insula Regions. Biological Psychiatry 2012, 72: 57-64. PMID: 22218286, PMCID: PMC3391585, DOI: 10.1016/j.biopsych.2011.11.022.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexGray matter volumeCumulative adversityPrefrontal cortexLife eventsSmaller gray matter volumeAnterior cingulateMatter volumeCingulate regionsRecent stressful life eventsCommunity participantsHealthy community participantsCumulative life eventsStressful life eventsStress-related psychopathologyAdverse life eventsAnterior cingulate regionsChronic stress effectsInsula regionsLife traumaKey prefrontalMedial prefrontalCommunity sampleOrbitofrontal cortexRight insula