2023
Greater stress and trauma mediate race-related differences in epigenetic age between Black and White young adults in a community sample
Holloway T, Harvanek Z, Xu K, Gordon D, Sinha R. Greater stress and trauma mediate race-related differences in epigenetic age between Black and White young adults in a community sample. Neurobiology Of Stress 2023, 26: 100557. PMID: 37501940, PMCID: PMC10369475, DOI: 10.1016/j.ynstr.2023.100557.Peer-Reviewed Original ResearchTraumatic eventsGrimAge accelerationMore traumatic eventsWhite participantsExploratory mediation analysisMajor life eventsImpact of stressAssaultive traumaPsychological dataCross-sectional sampleCommunity sampleLife eventsMediation analysisLifetime stressRace-related differencesChronic stressorsCumulative stressorsYoung adultsCumulative stressChronic illnessYoung adult populationStressorsGreater stressHealthy adultsParticipants
2022
Brain structural covariance network differences in adults with alcohol dependence and heavy‐drinking adolescents
Ottino‐González J, Garavan H, Albaugh M, Cao Z, Cupertino R, Schwab N, Spechler P, Allen N, Artiges E, Banaschewski T, Bokde A, Burke Quinlan E, Brühl R, Orr C, Cousijn J, Desrivières S, Flor H, Foxe J, Fröhner J, Goudriaan A, Gowland P, Grigis A, Heinz A, Hester R, Hutchison K, Li C, London E, Lorenzetti V, Luijten M, Nees F, Martín‐Santos R, Martinot J, Millenet S, Momenan R, Paillère Martinot M, Papadopoulos Orfanos D, Paulus M, Poustka L, Schmaal L, Schumann G, Sinha R, Smolka MN, Solowij N, Stein DJ, Stein EA, Uhlmann A, van Holst RJ, Veltman DJ, Walter H, Whelan R, Wiers RW, Yücel M, Zhang S, Jahanshad N, Thompson PM, Conrod P, Mackey S. Brain structural covariance network differences in adults with alcohol dependence and heavy‐drinking adolescents. Addiction 2022, 117: 1312-1325. PMID: 34907616, DOI: 10.1111/add.15772.Peer-Reviewed Original ResearchConceptsAlcohol dependenceHeavy drinking adolescentsStructural covariance networksAge 19Non-dependent controlsPre-existing risk factorsAge 14Cohort of adolescentsCross-sectional analysisRisk factorsAlcohol exposureEnhancing Neuroimaging GeneticsCortical thicknessHazardous drinkersEarly markerMeta-AnalysisNetwork segregationCross-sectional sampleIMAGEN studySubstantial exposureAdultsDrinking adolescentsCovariance networksBrain organizationAdolescents