Association of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis.
Tan B, Teo Y, Tan N, Yap D, Sundar R, Lee C, See A, Toh S. Association of obstructive sleep apnea and nocturnal hypoxemia with all-cancer incidence and mortality: a systematic review and meta-analysis. Journal Of Clinical Sleep Medicine 2022, 18: 1427-1440. PMID: 34755597, PMCID: PMC9059590, DOI: 10.5664/jcsm.9772.Peer-Reviewed Original ResearchConceptsAssociation of obstructive sleep apneaObstructive sleep apneaAll-cancer riskAll-cancer incidenceSevere nocturnal hypoxemiaNocturnal hypoxemiaSleep apneaAll-cancer mortalityModerate obstructive sleep apneaNo/mild OSASevere obstructive sleep apneaObstructive sleep apnea diagnosisObstructive sleep apnea treatmentOxygen desaturation indexMeta-analysisNewcastle-Ottawa ScaleSystematic reviewRandom-effects meta-analysesQuality of evidenceArousal indexDesaturation indexNormoxemic patientsRandomized studyHypoxemiaEvaluated study bias