383P RAS/AKT pathway mutations as predictive biomarkers in patients with colorectal cancer treated with the exportin 1 (XPO1) inhibitor selinexor (SEL) – inhibition of nuclear-cytoplasmic translocation of p27 as a mechanism of anti-tumour activity
Heong V, Koe P, Yong W, Soo R, Chee C, Wong A, Thian Y, Sundar R, Ho J, Gopinathan A, Lee S, Goh B, Tan D. 383P RAS/AKT pathway mutations as predictive biomarkers in patients with colorectal cancer treated with the exportin 1 (XPO1) inhibitor selinexor (SEL) – inhibition of nuclear-cytoplasmic translocation of p27 as a mechanism of anti-tumour activity. Annals Of Oncology 2016, 27: vi122. DOI: 10.1093/annonc/mdw368.26.Peer-Reviewed Original Research