Exhaustive acute exercise-induced ER stress is attenuated in IL-6-knockout mice
Pinto A, da Rocha A, Kohama E, Gaspar R, Simabuco F, Frantz F, de Moura L, Pauli J, Cintra D, Ropelle E, de Freitas E, da Silva A. Exhaustive acute exercise-induced ER stress is attenuated in IL-6-knockout mice. Journal Of Endocrinology 2019, 240: 181-193. PMID: 30400033, DOI: 10.1530/joe-18-0404.Peer-Reviewed Original ResearchConceptsIL-6 knockout miceExtensor digitorium longusPhysical exercise protocolAcute exercise protocolER stress proteinsExercise protocolIL-6WT groupIL-6 KO groupSerum levelsKO groupExercise-induced IL-6IL-6 concentrationsWild-type miceIntense physical exerciseER stressEndoplasmic reticulum stressStress proteinsIL-10Interleukin-6Knockout micePhysical exerciseSoleusHomeostatic functionsMice