2024
Stress-Induced Autonomic Dysfunction is Associated With Mental Stress–Induced Myocardial Ischemia in Patients With Coronary Artery Disease
Osei J, Vaccarino V, Wang M, Shah A, Lampert R, Li L, Ko Y, Pearce B, Kutner M, Garcia E, Piccinelli M, Raggi P, Bremner J, Quyyumi A, Sun Y, Ahmed H, Haddad G, Daaboul O, Roberts T, Stefanos L, Correia L, Shah A. Stress-Induced Autonomic Dysfunction is Associated With Mental Stress–Induced Myocardial Ischemia in Patients With Coronary Artery Disease. Circulation Cardiovascular Imaging 2024, 17: e016596. PMID: 38868952, PMCID: PMC11187646, DOI: 10.1161/circimaging.124.016596.Peer-Reviewed Original ResearchConceptsMental stress-induced myocardial ischemiaLow heart rate variabilityAssociated with MSIMICoronary artery diseaseAssociated with higher oddsStable coronary artery diseaseStress-induced myocardial ischemiaAutonomic dysfunctionLow-frequency heart rate variabilityArtery diseaseHeart rate variabilityHigher oddsHigher heart rate variabilityResponse to stressIndicator of autonomic dysfunctionMyocardial ischemiaSpeech stressorAssociated with adverse cardiovascular outcomesMultivariate logistic regression modelAssociation of autonomic dysfunctionAdverse cardiovascular outcomesLogistic regression modelsBlack participantsHolter monitoringClinical factorsHeart Rate Variability, Deceleration Capacity of Heart Rate, and Death: A Veteran Twins Study
Huang M, Shah A, Lampert R, Bliwise D, Johnson D, Clifford G, Sloan R, Goldberg J, Ko Y, Da Poian G, Perez‐Alday E, Almuwaqqat Z, Shah A, Garcia M, Young A, Moazzami K, Bremner J, Vaccarino V. Heart Rate Variability, Deceleration Capacity of Heart Rate, and Death: A Veteran Twins Study. Journal Of The American Heart Association 2024, 13: e032740. PMID: 38533972, PMCID: PMC11179789, DOI: 10.1161/jaha.123.032740.Peer-Reviewed Original ResearchMeSH KeywordsBradycardiaDecelerationElectrocardiography, AmbulatoryHeart RateHumansProspective StudiesVeteransConceptsLow-frequency heart rate variabilityHazard of deathAssociated with reduced mortality riskMortality riskMultivariable Cox frailty modelsHeart rate variabilityAssociated with decreased hazard of deathNational Death IndexDeceleration capacityAssociated with lower hazardWithin-pair analysesTwin studiesCox frailty modelsHazard ratio of deathRatio of deathDeceleration capacity of heart rateAssociated with decreased hazardDeath IndexHeart rateAll-cause deathHazard ratioFrequency domain heart rate variabilityStrong associations
2009
Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators
Lampert R, Shusterman V, Burg M, McPherson C, Batsford W, Goldberg A, Soufer R. Anger-Induced T-Wave Alternans Predicts Future Ventricular Arrhythmias in Patients With Implantable Cardioverter-Defibrillators. Journal Of The American College Of Cardiology 2009, 53: 774-778. PMID: 19245968, PMCID: PMC3979284, DOI: 10.1016/j.jacc.2008.10.053.Peer-Reviewed Original ResearchConceptsVentricular tachycardia/ventricular fibrillationFuture ventricular arrhythmiasT-wave alternansVentricular arrhythmiasVentricular fibrillationSpontaneous ventricular tachycardia/ventricular fibrillationHigher TWAImplantable cardioverter defibrillatorEjection fractionHighest quartileTWA testingWide QRSClinical arrhythmiaAmbulatory electrocardiographyLowest quartileFuture arrhythmiasSudden deathCardioverter defibrillatorClinical roleMultivariable regressionPatientsArrhythmiasRepolarization instabilityStress protocolSignificant predictors
2006
Electrophysiologic characteristics of anger-triggered arrhythmias
Stopper M, Joska T, Burg MM, Batsford WP, McPherson CA, Jain D, Lampert R. Electrophysiologic characteristics of anger-triggered arrhythmias. Heart Rhythm 2006, 4: 268-273. PMID: 17341385, DOI: 10.1016/j.hrthm.2006.11.003.Peer-Reviewed Original ResearchConceptsVentricular arrhythmiasElectrophysiologic characteristicsPolymorphic ventricular tachycardiaMood statesDisorganized rhythmInitial therapyAppropriate shocksVentricular tachycardiaArrhythmogenic substrateSudden deathArrhythmiasPatientsIntracardiac electrogramsElectrogramsPossible mechanismTime of shockInitiation patternsTachycardiaTherapyInitiationICD