2023
Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2021
Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage
Mazurek MH, Cahn BA, Yuen MM, Prabhat AM, Chavva IR, Shah JT, Crawford AL, Welch EB, Rothberg J, Sacolick L, Poole M, Wira C, Matouk CC, Ward A, Timario N, Leasure A, Beekman R, Peng TJ, Witsch J, Antonios JP, Falcone GJ, Gobeske KT, Petersen N, Schindler J, Sansing L, Gilmore EJ, Hwang DY, Kim JA, Malhotra A, Sze G, Rosen MS, Kimberly WT, Sheth KN. Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage. Nature Communications 2021, 12: 5119. PMID: 34433813, PMCID: PMC8387402, DOI: 10.1038/s41467-021-25441-6.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingNIH Stroke ScaleIntracerebral hemorrhageHematoma volumeYale-New Haven HospitalStroke care pathwayConventional magnetic resonance imagingBoard-certified neuroradiologistsNew Haven HospitalResource-limited settingsStroke ScaleClinical outcomesLow-field magnetic resonance imagingCare pathwayLow-field magnetic resonanceRadiological examinationConventional neuroimagingAdvanced MRI technologiesResonance imagingCases of disagreementHemorrhageMRI technologyPortable MRINeuroimagingMagnetic resonance
2019
Differential outcomes following successful resuscitation in cardiac arrest due to drug overdose
Ormseth CH, Maciel CB, Zhou SE, Barden MM, Miyares LC, Beekman RB, Gilmore EJ, Greer DM. Differential outcomes following successful resuscitation in cardiac arrest due to drug overdose. Resuscitation 2019, 139: 9-16. PMID: 30965094, DOI: 10.1016/j.resuscitation.2019.04.004.Peer-Reviewed Original ResearchConceptsCardiac arrestNeurological recoveryClinical characteristicsDrug overdoseBrain deathCerebral Performance Category scoreCA casesFavorable neurological recoverySimilar neurological recoveryLarge prospective studiesPositive toxicology screenRankin Scale scorePotential treatment optionSingle academic institutionBystander cardiopulmonary resuscitationHospital dischargeInpatient mortalitySuccessful resuscitationToxicology screenProspective studyTreatment optionsMedical recordsMedication administrationCardiopulmonary resuscitationRetrospective analysisDistinct predictive values of current neuroprognostic guidelines in post-cardiac arrest patients
Zhou SE, Maciel CB, Ormseth CH, Beekman R, Gilmore EJ, Greer DM. Distinct predictive values of current neuroprognostic guidelines in post-cardiac arrest patients. Resuscitation 2019, 139: 343-350. PMID: 30951843, PMCID: PMC6589093, DOI: 10.1016/j.resuscitation.2019.03.035.Peer-Reviewed Original ResearchConceptsPost-cardiac arrest patientsAmerican Heart AssociationArrest patientsPredictive valueDiffuse hypoxic-ischemic injurySingle tertiary care centerDistinct predictive valuesHypoxic-ischemic injuryOutcomes of patientsTertiary care centerLife-sustaining therapyIntensive care medicineFalse positive rateAAN guidelinesAHA guidelinesHospital recordsCardiac arrestHeart AssociationCare centerCurrent guidelinesCare medicineBetter outcomesBiochemical findingsPatientsAmerican Academy
2017
Clinical Reasoning
Beekman RB, Greer DM, Brooks DC, Maciel CB. Clinical Reasoning. Neurology 2017, 89: e239-e244. PMID: 29133614, DOI: 10.1212/wnl.0000000000004649.Peer-Reviewed Original Research