2008
Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates
Wisnewski AV, Liu Q, Liu J, Redlich CA. Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates. Clinical & Experimental Allergy 2008, 38: 957-967. PMID: 18498542, PMCID: PMC3131007, DOI: 10.1111/j.1365-2222.2008.02982.x.Peer-Reviewed Original ResearchMeSH KeywordsAdipokinesAdministration, InhalationAlbuminsAntigens, CDBlotting, WesternCells, CulturedChemokine CCL2Chitinase-3-Like Protein 1ChitinasesCyanatesEnzyme-Linked Immunosorbent AssayGene ExpressionGlycoproteinsHumansImmunity, InnateIntramolecular OxidoreductasesIsocyanatesLectinsLeukocytes, MononuclearLysosomesMacrophage Migration-Inhibitory FactorsMicroscopy, FluorescenceOligonucleotide Array Sequence AnalysisPolymerase Chain ReactionPolymorphism, GeneticProteinsRNAConceptsPeripheral blood mononuclear cellsInnate immune responseImmune responsePercentage of PBMCHuman peripheral blood mononuclear cellsFlow cytometrySystemic innate immune responseExposure-dependent decreaseMonocyte/macrophage traffickingHuman innate immune responseProtein expressionSpecific inhalation challengeBlood mononuclear cellsAdaptive immune responsesLow-density lipoproteinPattern recognition receptorsInhalation challengeOccupational asthmaClinical spectrumControl antigenMononuclear cellsHDI exposureSerum concentrationsAdaptive immunityGene/protein expression
2002
Wide distribution of Plasmodium ovale in Myanmar
Win T, Lin K, Mizuno S, Zhou M, Liu Q, Ferreira M, Tantular I, Kojima S, Ishii A, Kawamoto F. Wide distribution of Plasmodium ovale in Myanmar. Tropical Medicine And International Health 2002, 7: 231-239. PMID: 11903985, DOI: 10.1046/j.1365-3156.2002.00857.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnimalsChildChild, PreschoolDNA, ProtozoanFemaleHumansMalariaMaleMiddle AgedMyanmarPlasmodiumPolymerase Chain ReactionSpecies SpecificityConceptsPolymerase chain reactionPlasmodium ovaleP. ovaleP. ovale-infected patientsThin smearsPCR-positive patientsPlasmodium ovale infectionNested polymerase chain reactionHuman malaria parasiteSingle-species infectionsOvale infectionsP. malariaeQuadruple infectionsP. vivaxBlood samplesP. falciparumOvaleMalaria parasitesPatientsPlasmodium speciesInfectionChain reactionMolecular diagnosis
2000
Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates.
Liu Q, Ferreira M, Ndawi B, Ohmae H, Adagu I, Morikawa T, Horii T, Isomura S, Kawamoto F. Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates. The Southeast Asian Journal Of Tropical Medicine And Public Health 2000, 31: 808-17. PMID: 11414433.Peer-Reviewed Original Research
1998
Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania.
Ferreira M, Liu Q, Kimura M, Ndawi B, Tanabe K, Kawamoto F. Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania. Journal Of Parasitology 1998, 84: 1286-9. PMID: 9920333, DOI: 10.2307/3284693.Peer-Reviewed Original ResearchConceptsMerozoite surface protein 1MSP-1 gene typesSurface protein 1Type-specific polymerase chain reactionMajor malaria vaccine candidatePlasmodium falciparum infectionProtein 1Malaria vaccine candidateMsp-1 geneP. falciparum populationsMost patientsFalciparum infectionPolymerase chain reactionDistinct parasite populationsVaccine candidatesClinical isolatesAllelic typesGene typesPlasmodium falciparumNorthern TanzaniaChain reactionPatientsEpidemiological consequencesRecent findingsParasite populationsSequence Variation in the Small-Subunit rRNA Gene of Plasmodium malariae and Prevalence of Isolates with the Variant Sequence in Sichuan, China
Liu Q, Zhu S, Mizuno S, Kimura M, Liu P, Isomura S, Wang X, Kawamoto F. Sequence Variation in the Small-Subunit rRNA Gene of Plasmodium malariae and Prevalence of Isolates with the Variant Sequence in Sichuan, China. Journal Of Clinical Microbiology 1998, 36: 3378-3381. PMID: 9774600, PMCID: PMC105336, DOI: 10.1128/jcm.36.11.3378-3381.1998.Peer-Reviewed Original ResearchAllelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon.
Ferreira M, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura E, Katzin A, Isomura S, Kawamoto F. Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon. American Journal Of Tropical Medicine And Hygiene 1998, 59: 474-80. PMID: 9749647, DOI: 10.4269/ajtmh.1998.59.474.Peer-Reviewed Original ResearchConceptsMalaria-endemic areasSymptomatic malaria patientsAllelic typesMalaria patientsHypoendemic areaPolymerase chain reactionClinical isolatesP. falciparumMerozoite surface protein 1 geneGene typesPlasmodium falciparumProtein 1 geneVariable blocks 2Chain reactionPlasmodium falciparum merozoite surface protein 1 geneMerozoite surface protein-1 locusDirect sequencingContradictory dataFalciparumDistinct clonesIsolatesBlock 2Variable blocksHigh prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai‐Myanmar border, as revealed by acridine orange staining and PCR‐based diagnoses
Zhou M, Liu Q, Wongsrichanalai C, Suwonkerd W, Panart K, Prajakwong S, Pensiri A, Kimura M, Matsuoka H, Ferreira M, Isomura S, Kawamoto F. High prevalence of Plasmodium malariae and Plasmodium ovale in malaria patients along the Thai‐Myanmar border, as revealed by acridine orange staining and PCR‐based diagnoses. Tropical Medicine And International Health 1998, 3: 304-312. PMID: 9623932, DOI: 10.1046/j.1365-3156.1998.00223.x.Peer-Reviewed Original ResearchMeSH KeywordsAcridine OrangeAnimalsCross-Sectional StudiesDiagnosis, DifferentialFluorescent DyesHumansMalariaMyanmarPlasmodiumPlasmodium malariaePolymerase Chain ReactionPrevalenceThailandConceptsP. malariae infectionP. ovale infectionsP. malariaeThai-Myanmar borderMalaria patientsMalariae infectionOvale infectionsNew variant formAcridine orange staining methodHuman malaria parasitePlasmodium malariaeHigh prevalencePlasmodium ovaleTotal prevalenceP. ovaleP. malariae isolatesAcridine orange stainingMalariaeBurmese patientsInfectionMalaria parasitesPatientsThin smearsPrevalenceMixed infectionsStable Patterns of Allelic Diversity at the Merozoite Surface Protein‐1 Locus of Plasmodium falciparum in Clinical Isolates from Southern Vietnam
Ferreira M, Liu Q, Zhou M, Kimura M, Kaneko O, Van Thien H, Isomura S, Tanabe K, Kawamoto F. Stable Patterns of Allelic Diversity at the Merozoite Surface Protein‐1 Locus of Plasmodium falciparum in Clinical Isolates from Southern Vietnam. Journal Of Eukaryotic Microbiology 1998, 45: 131-136. PMID: 9495041, DOI: 10.1111/j.1550-7408.1998.tb05080.x.Peer-Reviewed Original ResearchConceptsPlasmodium falciparumFrequency-dependent immune selectionSame endemic areaMerozoite surface protein-1 locusSymptomatic patientsParasite populationsPolymerase chain reactionArea 17Endemic areasMesoendemic areaGene typesClinical isolatesAllelic typesPatientsImmune selectionDifferent gene typesChain reactionDistinct subpopulationsFalciparumPresent studyProtein-1 locusIsolatesPopulationPrevalenceAverage number