A pooled analysis of the LAMP assay for the detection of Neisseria meningitidis
Fan SJ, Tan HK, Xu YC, Chen YZ, Xie TA, Pan ZY, Ouyang S, Li Q, Li XY, Li ZX, Guo XG. A pooled analysis of the LAMP assay for the detection of Neisseria meningitidis. BMC Infectious Diseases 2020, 20: 525. PMID: 32689953, PMCID: PMC7372874, DOI: 10.1186/s12879-020-05250-w.Peer-Reviewed Original ResearchMeSH KeywordsData AccuracyHumansMeningitis, MeningococcalMolecular Diagnostic TechniquesNeisseria meningitidisNucleic Acid Amplification TechniquesPolymerase Chain ReactionROC CurveSensitivity and SpecificityConceptsLoop-mediated isothermal amplificationBacterial meningitisFunnel plotPublication biasHigh mortality rateLAMP assayWeb of ScienceSROC curvePooled analysisMortality rateClinical practiceDiagnostic accuracyMajor causeMeningococcusNeisseria meningitidisSummary receiverCharacteristic curveMeningitisReliable diagnosisDeeks' funnel plotIsothermal amplificationDepressed areasOriginal studyMeningitidisBacterial culturePooled analysis of the Xpert MTB/RIF assay for diagnosing tuberculous meningitis
Chen YZ, Sun LC, Wen YH, Li ZW, Fan SJ, Tan HK, Qiu M, Pan ZY, Li Q, Zhao YZ, Li ZX, Guo XG. Pooled analysis of the Xpert MTB/RIF assay for diagnosing tuberculous meningitis. Bioscience Reports 2020, 40: bsr20191312. PMID: 31778149, PMCID: PMC6946622, DOI: 10.1042/bsr20191312.Peer-Reviewed Original ResearchConceptsXpert MTB/RIFMTB/RIFTuberculous meningitisPositive likelihood ratioNegative likelihood ratioDiagnostic odds ratioOdds ratioEarly diagnosisCerebrospinal fluidCSF samplesPooled sensitivityLikelihood ratioReceiver operator characteristic curveOverall pooled sensitivityOperator characteristic curveExtrapulmonary tuberculosisDiagnostic delayPooled analysisSummary receiver operator characteristic curveDiagnostic efficacyClinical diagnosisMeningitisPooled specificityRelevant studiesDiagnosis