2011
Metadata-driven Software Systems in Biomedicine, Designing Systems that can adapt to Changing Knowledge
Nadkarni P. Metadata-driven Software Systems in Biomedicine, Designing Systems that can adapt to Changing Knowledge. Health Informatics 2011 DOI: 10.1007/978-0-85729-510-1.Peer-Reviewed Original ResearchSoftware systemsClinical study data management systemsBiomedical database systemsData management systemResearch support systemSoftware developmentDatabase schemaDatabase systemsExtensible designSoftware historyDesigning systemSupport systemManagement systemSuch systemsDevelopment skillsElectronic medical recordsNon-trivial examplesNew systemProblems oneBest systemDetailed projectMetadataOntologyCase studySystem
2009
Automated Database Mediation Using Ontological Metadata Mappings
Marenco L, Wang R, Nadkarni P. Automated Database Mediation Using Ontological Metadata Mappings. Journal Of The American Medical Informatics Association 2009, 16: 723-737. PMID: 19567801, PMCID: PMC2744723, DOI: 10.1197/jamia.m3031.Peer-Reviewed Original ResearchConceptsCross-database queriesHigh-level rulesEnforcement of constraintsDatabase MediationDatabase federationsDatabase ontologyExtended metadataGranularity levelsMetadata mappingBiomedical ontologiesDifferent granularitiesFramework simplifiesCategories of dataMaintenance of systemsMapping rulesQueriesDatabase informationGranularity of representationGlobal vocabularyOntologyGranularityIntegrator systemMetadataDatabaseSNOMED
2004
QIS: A Framework for Biomedical Database Federation
Marenco L, Wang TY, Shepherd G, Miller PL, Nadkarni P. QIS: A Framework for Biomedical Database Federation. Journal Of The American Medical Informatics Association 2004, 11: 523-534. PMID: 15298995, PMCID: PMC524633, DOI: 10.1197/jamia.m1506.Peer-Reviewed Original ResearchConceptsNetwork-based serversHeterogeneous data sourcesRobust data integrationIntegration serverOntology serverDatabase federationsSource serverNeuroscience databasesData integrationMediator frameworkServerData elementsQueriesData sourcesMetadataPrototype stageStandard technologyIntegrator systemGenomic databasesFrameworkDatabaseOntologyArchitectureSchemaTechnological expertise