2023
Longitudinal Comparative Analysis of Complications and Subsequent Interventions Following Stand-Alone Interspinous Spacers, Open Decompression, or Fusion for Lumbar Stenosis
Whang P, Tran O, Rosner H. Longitudinal Comparative Analysis of Complications and Subsequent Interventions Following Stand-Alone Interspinous Spacers, Open Decompression, or Fusion for Lumbar Stenosis. Advances In Therapy 2023, 40: 3512-3524. PMID: 37289411, PMCID: PMC10329952, DOI: 10.1007/s12325-023-02562-6.Peer-Reviewed Original ResearchConceptsLong-term complicationsLumbar spinal stenosisLumbar spine surgeryFirst surgical interventionLife-threatening eventsSurgical interventionISD patientsSurgery cohortOpen decompressionOpen surgerySpine surgerySubsequent interventionsComplication-related costsOpen surgery cohortSubsequent surgical interventionInterspinous spacer devicesFusion cohortLSS patientsConservative therapyBaseline characteristicsPatient agePostoperative outcomesLumbar stenosisSpinal stenosisMedicare database
2021
HPyV6‐ and HPyV7‐negative parakeratosis and dyskeratosis in squamous cell carcinoma in situ
Ko CJ, Wang A, Panse G, Lee EE, Wang RC, Whang PG, Bosenberg M, Damsky W. HPyV6‐ and HPyV7‐negative parakeratosis and dyskeratosis in squamous cell carcinoma in situ. Journal Of Cutaneous Pathology 2021, 48: 998-1000. PMID: 33813761, DOI: 10.1111/cup.14022.Peer-Reviewed Original Research
2020
Evidence-Based Recommendations for Spine Surgery.
Fisher CG, Vaccaro AR, Patel AA, Whang PG, Thomas KC, Chi J, Mulpuri K, Prasad SK. Evidence-Based Recommendations for Spine Surgery. Spine 2020, 45: 851-859. PMID: 32355150, DOI: 10.1097/brs.0000000000003512.Peer-Reviewed Original ResearchConceptsSpine surgeryDecompression surgeryLumbar decompression surgerySpinal decompression surgeryPost-operative MRISagittal spinopelvic alignmentEvidence-based recommendationsLumbar disc arthroplastyLumbar surgeryPrognostic factorsTranexamic acidOsteoporotic patientsDisc arthroplastySpinopelvic alignmentSurgeryClinical practiceComparative effectivenessPatientsArthroplastyRecommendationsFusion supportMRI
2017
Predictors of Outcome in Conservative and Minimally Invasive Surgical Management of Pain Originating From the Sacroiliac Joint
Dengler J, Duhon B, Whang P, Frank C, Glaser J, Sturesson B, Garfin S, Cher D, Rendahl A, Polly D. Predictors of Outcome in Conservative and Minimally Invasive Surgical Management of Pain Originating From the Sacroiliac Joint. Spine 2017, 42: 1664-1673. PMID: 28350586, PMCID: PMC5636200, DOI: 10.1097/brs.0000000000002169.Peer-Reviewed Original ResearchConceptsOswestry Disability IndexPredictors of outcomeSIJ fusionVisual analog scaleInvasive surgical managementSacroiliac jointSIJ painTreatment outcomesConservative managementProspective trialSurgical managementSingle-arm prospective trialInvasive SIJ fusionLonger pain durationLower patient ageInvasive surgical treatmentIndividual patient dataPatient-level analysisTriangular titanium implantsBetter treatment outcomesAnalysis of predictorsRandom-effects modelMultivariate regression analysisTrial sample sizeNonopioid users
2015
Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs Nonsurgical Management for Sacroiliac Joint Dysfunction: 12-Month Outcomes
Polly DW, Cher DJ, Wine KD, Whang PG, Frank CJ, Harvey CF, Lockstadt H, Glaser JA, Limoni RP, Sembrano JN. Randomized Controlled Trial of Minimally Invasive Sacroiliac Joint Fusion Using Triangular Titanium Implants vs Nonsurgical Management for Sacroiliac Joint Dysfunction: 12-Month Outcomes. Neurosurgery 2015, 77: 674-691. PMID: 26291338, PMCID: PMC4605280, DOI: 10.1227/neu.0000000000000988.Peer-Reviewed Original ResearchConceptsTriangular titanium implantsQuality of lifeSacroiliac joint dysfunctionSurgical groupNonsurgical managementSIJ dysfunctionSIJ fusionJoint dysfunctionOswestry Disability Index improvementSix-month success rateInvasive Sacroiliac Joint FusionChronic SIJ dysfunctionInvasive SIJ fusionNonsurgical management groupsOswestry Disability IndexSacroiliac joint fusionLow back painRandomized Controlled TrialsLevel 1 studiesSuccess rateTitanium implantsDegenerative sacroiliitisSIJ disruptionDisability IndexSIJ painSuperion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Davis RP, Miller LE, Block JE, Geisler FH. Superion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis. Spine 2015, 40: 275-282. PMID: 25494323, DOI: 10.1097/brs.0000000000000735.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisIntermittent neurogenic claudicationInterspinous process spacerNeurogenic claudicationClinical successSpinal stenosisModerate lumbar spinal stenosisPrimary composite endpointRate of complicationsMajority of patientsInvasive treatment alternativeConservative careLeg painSurgical decompressionControl patientsMost patientsComposite endpointNonsurgical managementHigh quality comparative dataPatient complaintsNoninferiority trialBACKGROUND DATAClaudicationInterspinous spacerPatients
2014
Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Miller LE, Block JE, Geisler FH. Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis. BMC Musculoskeletal Disorders 2014, 15: 221. PMID: 24996648, PMCID: PMC4109165, DOI: 10.1186/1471-2474-15-221.Peer-Reviewed Original ResearchMeSH KeywordsAgedBack PainDisability EvaluationEquipment DesignFemaleHumansLumbar VertebraeMaleOrthopedic ProceduresPain MeasurementPain, PostoperativePatient SatisfactionPredictive Value of TestsProspective StudiesRadiographyRecovery of FunctionSpinal StenosisSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesConceptsModerate lumbar spinal stenosisLumbar spinal stenosisConservative careInterspinous spacerClinical outcomesSpinal stenosisBack functionTwo-year clinical outcomesOswestry Disability IndexPhysical function scoresPatient-reported outcomesInvasive surgical alternativePatient satisfaction scoresExtremity painAxial painDisability IndexComplication dataFunction scoresSurgical alternativePatientsSatisfaction scoresSymptom severityPainIndex levelMulticenter
2013
Comparison of Axial and Anterior Interbody Fusions of the L5–S1 Segment
Whang PG, Sasso RC, Patel VV, Ali RM, Fischgrund JS. Comparison of Axial and Anterior Interbody Fusions of the L5–S1 Segment. Clinical Spine Surgery A Spine Publication 2013, 26: 437-443. PMID: 24196923, DOI: 10.1097/bsd.0b013e318292aad7.Peer-Reviewed Original ResearchConceptsAnterior lumbar interbody fusionAdverse eventsInterbody fusionPosterior fixationDevice-related adverse eventsL5-S1 interbody fusionL5-S1 disc spaceAnterior interbody fusionAnterior retroperitoneal approachSerious intraoperative complicationsAnterior column supportDifferent surgical approachesLumbar interbody fusionRadiographic fusion rateL5-S1 segmentSupplemental posterior fixationAxiaLIF techniqueHospital chartsIntraoperative complicationsMulticenter reviewRadiographic successRetroperitoneal approachArthrodesis ratesPresacral spaceProcedural data
2011
Cement Augmentation of Refractory Osteoporotic Vertebral Compression Fractures
Gerling MC, Eubanks JD, Patel R, Whang PG, Bohlman HH, Ahn NU. Cement Augmentation of Refractory Osteoporotic Vertebral Compression Fractures. Spine 2011, 36: e1266-e1269. PMID: 21358465, DOI: 10.1097/brs.0b013e31820a0b3f.Peer-Reviewed Original ResearchConceptsOsteoporotic vertebral compression fracturesInpatient pain managementVertebral compression fracturesCement augmentationPain managementBed restCompression fracturesNumber of fracturesProportional hazards regression modelsConservative pain managementIntractable back painNational Death IndexCement augmentation proceduresHigh-energy traumaSignificant survival advantageHazards regression modelsHigh-dose narcoticsKaplan-Meier plotsUniversity Hospital databaseExact Fisher testMann-Whitney testAggressive managementConservative treatmentElderly patientsChart review
2010
Normal Functional Range of Motion of the Cervical Spine During 15 Activities of Daily Living
Bible JE, Biswas D, Miller CP, Whang PG, Grauer JN. Normal Functional Range of Motion of the Cervical Spine During 15 Activities of Daily Living. Clinical Spine Surgery A Spine Publication 2010, 23: 15-21. PMID: 20051924, DOI: 10.1097/bsd.0b013e3181981632.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAgedAnthropometryArthrographyArthrometry, ArticularBiomechanical PhenomenaCervical VertebraeCineradiographyFemaleHead MovementsHumansIntervertebral DiscMaleMiddle AgedMovementNeck MusclesProspective StudiesRange of Motion, ArticularReference ValuesYoung AdultZygapophyseal JointConceptsFull active ROMAsymptomatic subjectsCervical spineCervical ROMActive ROMFunctional ROMDaily livingFlexion/extensionProspective clinical studyLateral bending radiographsNormal cervical rangeDynamic flexion/extensionNormal functional rangeIntraclass correlation coefficientPreoperative impairmentCervical rangePostsurgical outcomesCervical motionClinical studiesBACKGROUND DATASpinal ROMConsecutive daysRadiographic measurementsADLGreater ROM
2009
The Management of Spinal Injuries in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis
Whang PG, Goldberg G, Lawrence JP, Hong J, Harrop JS, Anderson DG, Albert TJ, Vaccaro AR. The Management of Spinal Injuries in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis. Clinical Spine Surgery A Spine Publication 2009, 22: 77-85. PMID: 19342927, DOI: 10.1097/bsd.0b013e3181679bcb.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overComorbidityDisability EvaluationFemaleHumansHyperostosis, Diffuse Idiopathic SkeletalMaleMiddle AgedMortalityNeurosurgical ProceduresOutcome Assessment, Health CarePostoperative ComplicationsRadiographyRetrospective StudiesSpinal Cord CompressionSpinal FracturesSpinal InjuriesSpineSpondylitis, AnkylosingTreatment OutcomeConceptsDiffuse idiopathic skeletal hyperostosisIdiopathic skeletal hyperostosisSpinal injuryDISH patientsNeurologic deficitsClinical outcomesAS patientsSkeletal hyperostosisAmerican Spinal Injury Association Impairment ScaleHalo-vest orthosisOverall complication rateHalo-vest immobilizationAppropriate imaging studiesSpinal cord injurySubaxial cervical spineOdom's criteriaNonoperative treatmentComplication rateNeurologic injuryNeurologic statusASIA ARetrospective reviewOperative managementCord injurySingle institution
2008
Financial Incentives for Lumbar Surgery: A Critical Analysis of Physician Reimbursement for Decompression and Fusion Procedures
Whang PG, Lim MR, Sasso RC, Skelton A, Brown ZB, Anderson D, Albert TJ, Hilibrand AS, Vaccaro AR. Financial Incentives for Lumbar Surgery: A Critical Analysis of Physician Reimbursement for Decompression and Fusion Procedures. Clinical Spine Surgery A Spine Publication 2008, 21: 381-386. PMID: 18679090, DOI: 10.1097/bsd.0b013e31814d4e1b.Peer-Reviewed Original ResearchConceptsInstrumented fusion proceduresFusion proceduresIsolated decompressionAutogenous iliac crest boneSingle-level decompressionIliac crest boneLumbar degenerative conditionsLumbar decompressionLumbar surgeryPostoperative visitDecompression groupSingle surgeonConsecutive seriesOffice chartsOperative reportsPosterolateral fusionSurgical timeTotal clinical timeCrest boneLumbar degenerationSpinal fusionBACKGROUND DATALumbar arthrodesisType of operationSpine surgeons
2007
The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study
Vaccaro AR, Whang PG, Patel T, Phillips FM, Anderson DG, Albert TJ, Hilibrand AS, Brower RS, Kurd MF, Appannagari A, Patel M, Fischgrund JS. The safety and efficacy of OP-1 (rhBMP-7) as a replacement for iliac crest autograft for posterolateral lumbar arthrodesis: minimum 4-year follow-up of a pilot study. The Spine Journal 2007, 8: 457-465. PMID: 17588821, DOI: 10.1016/j.spinee.2007.03.012.Peer-Reviewed Original ResearchConceptsOP-1 PuttyUninstrumented fusionIliac crest autograftDegenerative spondylolisthesisOverall success rateAutograft patientsX-ray filmsAdverse eventsDecompressive laminectomyCrest autograftAutogenous boneShort Form Health Survey scoresForm Health Survey scoresBone graft substituteAutogenous iliac crest bone graftIliac crest bone graftPatient-reported outcome measuresPilot studyIntermediate-term efficacyOswestry Disability IndexPreoperative Oswestry scoreHealth Survey scoresPrimary efficacy endpointSF-36 scoresSymptomatic spinal stenosis