2023
Longitudinal Comparative Analysis of Complications and Subsequent Interventions Following Stand-Alone Interspinous Spacers, Open Decompression, or Fusion for Lumbar Stenosis
Whang P, Tran O, Rosner H. Longitudinal Comparative Analysis of Complications and Subsequent Interventions Following Stand-Alone Interspinous Spacers, Open Decompression, or Fusion for Lumbar Stenosis. Advances In Therapy 2023, 40: 3512-3524. PMID: 37289411, PMCID: PMC10329952, DOI: 10.1007/s12325-023-02562-6.Peer-Reviewed Original ResearchConceptsLong-term complicationsLumbar spinal stenosisLumbar spine surgeryFirst surgical interventionLife-threatening eventsSurgical interventionISD patientsSurgery cohortOpen decompressionOpen surgerySpine surgerySubsequent interventionsComplication-related costsOpen surgery cohortSubsequent surgical interventionInterspinous spacer devicesFusion cohortLSS patientsConservative therapyBaseline characteristicsPatient agePostoperative outcomesLumbar stenosisSpinal stenosisMedicare databaseQuantifying the Long-Term Impact of a Motion-Sparing Interspinous Spacer on Sagittal Alignment in Patients with Lumbar Spinal Stenosis
Whang P, Chen L, Jain R. Quantifying the Long-Term Impact of a Motion-Sparing Interspinous Spacer on Sagittal Alignment in Patients with Lumbar Spinal Stenosis. Interventional Pain Medicine 2023, 2: 100236. DOI: 10.1016/j.inpm.2023.100236.Peer-Reviewed Original Research
2017
Interspinous implants to treat spinal stenosis
Gala RJ, Russo GS, Whang PG. Interspinous implants to treat spinal stenosis. Current Reviews In Musculoskeletal Medicine 2017, 10: 182-188. PMID: 28324328, PMCID: PMC5435644, DOI: 10.1007/s12178-017-9413-8.Peer-Reviewed Original ResearchSpinal stenosisInterspinous spacerModerate spinal stenosisOpen decompressive surgeryLumbar spinal stenosisPedicle screw instrumentationFormal decompressionSuperion deviceDecompressive surgerySignificant morbidityPatient selectionInvasive optionInvasive strategyImproved outcomesInterspinous implantStenosisDecompressionInterspinous spaceSpinal anatomyCoflex deviceOutcomesImplantsMorbidityComplicationsPatients
2015
Superion® InterSpinous Spacer for treatment of moderate degenerative lumbar spinal stenosis: durable three-year results of a randomized controlled trial
Patel VV, Nunley PD, Whang PG, Haley TR, Bradley WD, Davis RP, Block JE, Geisler FH. Superion® InterSpinous Spacer for treatment of moderate degenerative lumbar spinal stenosis: durable three-year results of a randomized controlled trial. Journal Of Pain Research 2015, Volume 8: 657-662. PMID: 26491369, PMCID: PMC4599047, DOI: 10.2147/jpr.s92633.Peer-Reviewed Original ResearchDegenerative lumbar spinal stenosisLumbar spinal stenosisPrimary composite endpointSpinal stenosisComposite endpointClinical outcomesDrug Administration Investigational Device Exemption trialDisease-specific functional outcomesInvestigational device exemption trialDurable clinical improvementLeg pain severityRandomized study groupsZurich Claudication QuestionnaireProcedure-related complicationsIntermittent neurogenic claudicationTreatment of patientsProportion of subjectsThree-year resultsTreatment of subjectsIndividual patient successNeurogenic claudicationPrimary endpointClinical improvementCorresponding success ratesPain severitySuperion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Davis RP, Miller LE, Block JE, Geisler FH. Superion Interspinous Process Spacer for Intermittent Neurogenic Claudication Secondary to Moderate Lumbar Spinal Stenosis. Spine 2015, 40: 275-282. PMID: 25494323, DOI: 10.1097/brs.0000000000000735.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisIntermittent neurogenic claudicationInterspinous process spacerNeurogenic claudicationClinical successSpinal stenosisModerate lumbar spinal stenosisPrimary composite endpointRate of complicationsMajority of patientsInvasive treatment alternativeConservative careLeg painSurgical decompressionControl patientsMost patientsComposite endpointNonsurgical managementHigh quality comparative dataPatient complaintsNoninferiority trialBACKGROUND DATAClaudicationInterspinous spacerPatients
2014
Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis
Patel VV, Whang PG, Haley TR, Bradley WD, Nunley PD, Miller LE, Block JE, Geisler FH. Two-year clinical outcomes of a multicenter randomized controlled trial comparing two interspinous spacers for treatment of moderate lumbar spinal stenosis. BMC Musculoskeletal Disorders 2014, 15: 221. PMID: 24996648, PMCID: PMC4109165, DOI: 10.1186/1471-2474-15-221.Peer-Reviewed Original ResearchMeSH KeywordsAgedBack PainDisability EvaluationEquipment DesignFemaleHumansLumbar VertebraeMaleOrthopedic ProceduresPain MeasurementPain, PostoperativePatient SatisfactionPredictive Value of TestsProspective StudiesRadiographyRecovery of FunctionSpinal StenosisSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesConceptsModerate lumbar spinal stenosisLumbar spinal stenosisConservative careInterspinous spacerClinical outcomesSpinal stenosisBack functionTwo-year clinical outcomesOswestry Disability IndexPhysical function scoresPatient-reported outcomesInvasive surgical alternativePatient satisfaction scoresExtremity painAxial painDisability IndexComplication dataFunction scoresSurgical alternativePatientsSatisfaction scoresSymptom severityPainIndex levelMulticenter
2013
Midterm Outcomes of a Prospective Multicenter Randomized Controlled Trial Comparing the Clinical Efficacy of Interspinous Spacers as a Treatment for Moderate Lumbar Spinal Stenosis
Whang P, Patel V, Bradley W, Block J. Midterm Outcomes of a Prospective Multicenter Randomized Controlled Trial Comparing the Clinical Efficacy of Interspinous Spacers as a Treatment for Moderate Lumbar Spinal Stenosis. The Spine Journal 2013, 13: s136-s137. DOI: 10.1016/j.spinee.2013.07.352.Peer-Reviewed Original ResearchMitigating Adverse Event Reporting Bias in Spine Surgery
Auerbach JD, McGowan KB, Halevi M, Gerling MC, Sharan AD, Whang PG, Maislin G. Mitigating Adverse Event Reporting Bias in Spine Surgery. Journal Of Bone And Joint Surgery 2013, 95: 1450-1456. PMID: 23965694, DOI: 10.2106/jbjs.l.00251.Peer-Reviewed Original ResearchConceptsIndependent clinical events committeeClinical events committeeAdverse eventsClinical trialsLevels of severityInvestigational device exemption studyFuture clinical trialsAdverse event dataLumbar spinal fusionAdverse event reportingAdverse event reportsSpinal stenosisEvents committeeSafety profileSurgery StudyFusion groupInvestigator biasSpine surgerySpinal fusionSpine surgeonsSurgeryInvestigational deviceStudy sponsorEvent reportingFinancial interestsLumbar spinal stenosis.
Lee JY, Whang PG, Lee JY, Phillips FM, Patel AA. Lumbar spinal stenosis. Instructional Course Lectures 2013, 62: 383-96. PMID: 23395043.Peer-Reviewed Original ResearchConceptsLumbar spinal stenosisSpinal stenosisNonsurgical treatment optionsOptimal treatment approachEvidence-based outcomesTreatment optionsDiagnostic workupPatient presentationSpinal surgeryCommon reasonElderly populationTreatment approachesSurgical innovationStenosisPatientsSurgeryPathophysiologyWorkupDiseaseDiagnosis
2011
Interspinous Spacers for Lumbar Spinal Stenosis
Long W, Whang P. Interspinous Spacers for Lumbar Spinal Stenosis. Operative Techniques In Orthopaedics 2011, 21: 208-212. DOI: 10.1053/j.oto.2011.08.001.Peer-Reviewed Original ResearchInterspinous spacerNeurogenic claudicationSpinal stenosisAdditional prospective clinical trialsProspective clinical trialsIntermittent neurogenic claudicationAppropriate imaging studiesLumbar spinal stenosisSignificant functional disabilityNumber of complicationsPostural reliefSymptomatic LSSNeurologic sequelaePersistent symptomsPosterior decompressionFunctional disabilitySurgical interventionConservative measuresInvasive optionSpinal canalClinical trialsSurgical techniqueOperative procedureClinical investigationLumbar flexion