DNA replication in the autonomous parvoviruses
Cotmore S, Tattersall* P. DNA replication in the autonomous parvoviruses. Seminars In Virology 1995, 6: 271-281. DOI: 10.1006/smvy.1995.0033.Peer-Reviewed Original ResearchShort palindromic sequencesSpecific origin sequencesUnit-length genomesDNA synthesisViral NS1 proteinProgeny DNA synthesisLeading-strand synthesisSingle-strand nicksDNA replicationDNA genomeOrigin sequencesPalindromic sequenceAutonomous parvovirusesGenomeNew copiesNS1 proteinTelomeresReplicationOngoing replicationSequence Motifs in the Replicator Protein of Parvovirus MVM Essential for Nicking and Covalent Attachment to the Viral Origin: Identification of the Linking Tyrosine
Nüesch J, Cotmore S, Tattersall P. Sequence Motifs in the Replicator Protein of Parvovirus MVM Essential for Nicking and Covalent Attachment to the Viral Origin: Identification of the Linking Tyrosine. Virology 1995, 209: 122-135. PMID: 7747462, DOI: 10.1006/viro.1995.1236.Peer-Reviewed Original ResearchConceptsMutant proteinsRolling-circle replicationTyrosine motifOrigin-containing plasmidParvoviral DNA replicationViral originParvovirus minute virusSingle-strand nicksInitiator proteinSequence motifsDNA replicationSite-specific bindingSequence comparisonCyanogen bromide cleavageOrigin sequencesDe novo synthesisSubstrate DNAY210Circle replicationLatter residueStrand nicksHeLa cellsLow salt conditionsCommon motifMetal coordination sites