2023
Purpose in life protects against the development of suicidal thoughts and behaviors in U.S. veterans without a history of suicidality: A 10-year, nationally representative, longitudinal study
Fischer I, Nichter B, Feldman D, Na P, Tsai J, Harpaz-Rotem I, Schulenberg S, Pietrzak R. Purpose in life protects against the development of suicidal thoughts and behaviors in U.S. veterans without a history of suicidality: A 10-year, nationally representative, longitudinal study. Journal Of Affective Disorders 2023, 340: 551-554. PMID: 37557988, DOI: 10.1016/j.jad.2023.08.040.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingHumansLongitudinal StudiesProspective StudiesRisk FactorsSuicidal IdeationSuicideVeteransConceptsIncident suicidal ideationAlcohol use disorderIncident suicide attemptsCurrent alcohol use disorderHistory of STBSuicidal ideationSuicide attemptsBaseline predictorsDaily livingPopulation-based prospective cohort studySuicidal thoughtsLow purposeCurrent posttraumatic stress disorderProspective cohort studyTraditional risk factorsLower annual household incomeMultivariable regression analysisEvidence-based interventionsUS military veteransPosttraumatic stress disorderAnnual household incomeCohort studyTrauma burdenRisk factorsNational HealthLongitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic
Fischer I, Nichter B, Na P, Norman S, Krystal J, Pietrzak R. Longitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic. JAMA Psychiatry 2023, 80: 577-584. PMID: 37017978, PMCID: PMC10077136, DOI: 10.1001/jamapsychiatry.2023.0393.Peer-Reviewed Original ResearchConceptsNew-onset suicidal ideationUS military veteransLifetime substance use disorderPast-year suicidal ideationSubstance use disordersSuicidal ideationSuicide planningMilitary veteransUse disordersPsychiatric distressCOVID-19 pandemicSuicidal thoughtsPopulation-based longitudinal studyEvidence-based preventionLongitudinal studyLongitudinal trendsCohort studyNational HealthUS veteransMAIN OUTCOMEVeterans StudySuicide attemptsSuicide riskVulnerable populationsVeteransPrevalence, Correlates, and Psychiatric Burden of Prolonged Grief Disorder in U.S. Military Veterans: Results From a Nationally Representative Study
Na P, Fischer I, Shear K, Pietrzak R. Prevalence, Correlates, and Psychiatric Burden of Prolonged Grief Disorder in U.S. Military Veterans: Results From a Nationally Representative Study. American Journal Of Geriatric Psychiatry 2023, 31: 543-548. PMID: 36878740, PMCID: PMC11143540, DOI: 10.1016/j.jagp.2023.02.007.Peer-Reviewed Original ResearchConceptsIndependent risk factorMajor depressive disorderUnited States veteransCoronavirus disease 2019Substance use disordersPost-traumatic stress disorderGrief disorderAdverse childhood experiencesNon-natural causesU.S. military veteransPoint prevalenceNationally Representative StudyFemale sexNational HealthRepresentative studyRisk factorsDepressive disorderPsychiatric burdenDisease 2019States veteransAdditional adjustmentPsychiatric disordersProlonged Grief DisorderUse disordersU.S. veterans
2022
Durkheim's Theory of Social Integration and Suicide Revisited: Is It Diversity of Social Networks or Perceived Strength of Social Support That Matters?
Na P, Bommersbach T, Pietrzak R, Rhee T. Durkheim's Theory of Social Integration and Suicide Revisited: Is It Diversity of Social Networks or Perceived Strength of Social Support That Matters? The Journal Of Clinical Psychiatry 2022, 84 PMID: 36479956, DOI: 10.4088/jcp.22m14477.Peer-Reviewed Original ResearchGenetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden
Nichter B, Koller D, De Angelis F, Wang J, Girgenti M, Na P, Hill M, Norman S, Krystal J, Gelernter J, Polimanti R, Pietrzak R. Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden. Psychological Medicine 2022, 53: 6325-6333. PMID: 36444557, DOI: 10.1017/s0033291722003646.Peer-Reviewed Original ResearchMeSH KeywordsFemaleGenome-Wide Association StudyHumansMaleRisk FactorsSuicidal IdeationSuicide, AttemptedVeteransConceptsPolygenic risk scoresUS military veteransLifetime suicide attemptsSuicide attemptsTrauma exposureTrauma burdenGenetic liabilityMilitary veteransDrug repurposing analysisPopulation-based sampleCumulative trauma exposureLifetime trauma exposureLow trauma exposureSuicide prediction modelsChronic inflammationInflammatory processNervous system developmentRisk scorePsychiatric characteristicsSuicidal behaviorExposure interactionsLarge genome-wide association studiesHigh levelsVeteransSuicidalityIdentifying factors associated with elevated suicidal intent among U.S. military veterans
Nichter B, Na PJ, Stanley IH, Marx BP, Herzog S, Moynahan V, Hill ML, Norman SB, Pietrzak RH. Identifying factors associated with elevated suicidal intent among U.S. military veterans. Journal Of Psychiatric Research 2022, 155: 68-74. PMID: 35988305, DOI: 10.1016/j.jpsychires.2022.08.001.Peer-Reviewed Original ResearchMeSH KeywordsChildHumansMilitary PersonnelPrevalenceRisk FactorsSex OffensesSuicidal IdeationSuicide, AttemptedVeteransConceptsSuicidal intentU.S. military veteransHigh riskU.S. veteransPast-year suicidal ideationMilitary veteransPopulation-based sampleCurrent suicidal intentPrior suicide attemptsRisk factorsNational HealthCurrent insomniaCurrent depressionSuicidal ideationVeterans StudyVulnerability factorsSuicide attemptsSuicidal behaviorChildhood sexual abuseCo-occurring factorsSuicide mortalityVeterans' reportsSpecific vulnerability factorVeteransRepresentative sampleAssociation of Distress Due to Systemic Racism and Racial Disparities With Psychopathology and Suicidal Ideation Among US Veterans During the COVID-19 Pandemic.
Jegede O, Na PJ, Haeny AM, Krystal JH, Pietrzak RH. Association of Distress Due to Systemic Racism and Racial Disparities With Psychopathology and Suicidal Ideation Among US Veterans During the COVID-19 Pandemic. The Journal Of Clinical Psychiatry 2022, 83 PMID: 35921504, PMCID: PMC10228546, DOI: 10.4088/jcp.22br14410.Peer-Reviewed Original ResearchFactors Associated With Remission of Suicidal Ideation During the COVID-19 Pandemic: A Population-Based, Longitudinal Study in US Military Veterans.
Herzog S, Nichter B, Hill ML, Na PJ, Norman SB, Pietrzak RH. Factors Associated With Remission of Suicidal Ideation During the COVID-19 Pandemic: A Population-Based, Longitudinal Study in US Military Veterans. The Journal Of Clinical Psychiatry 2022, 83 PMID: 35771973, DOI: 10.4088/jcp.21br14341.Peer-Reviewed Original ResearchMental Health Burden in Enlisted and Commissioned U.S. Military Veterans: Importance of Indirect Trauma Exposure in Commissioned Veterans
Merians AN, Na PJ, Tsai J, Harpaz-Rotem I, Pietrzak RH. Mental Health Burden in Enlisted and Commissioned U.S. Military Veterans: Importance of Indirect Trauma Exposure in Commissioned Veterans. Psychiatry 2022, 85: 418-432. PMID: 35532217, DOI: 10.1080/00332747.2022.2068301.Peer-Reviewed Original ResearchMeSH KeywordsDepressive Disorder, MajorHumansMental HealthStress Disorders, Post-TraumaticSubstance-Related DisordersSuicidal IdeationVeteransConceptsPosttraumatic stress disorderMajor depressive disorderU.S. military veteransSuicidal ideationMilitary veteransTrauma exposureMost mental health outcomesMental health burdenPast-year suicidal ideationDrug use disordersU.S. veteran populationMental health historyHigh exposureMental health outcomesMultivariable analysisDepressive disorderNational HealthHealth burdenPost-stratification weightsUse disordersVeteran populationHealth historyHealth outcomesIndirect trauma exposureVeterans StudyCo-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone.
Na PJ, Scodes J, Fishman M, Rotrosen J, Nunes EV. Co-occurring Depression and Suicidal Ideation in Opioid Use Disorder: Prevalence and Response During Treatment With Buprenorphine-Naloxone and Injection Naltrexone. The Journal Of Clinical Psychiatry 2022, 83 PMID: 35452194, DOI: 10.4088/jcp.21m14140.Peer-Reviewed Original ResearchConceptsOpioid use disorderWeeks of treatmentBuprenorphine-naloxoneCo-occurring depressionSevere depressionWeek 4Mild depressionUse disordersSuicidal ideationMedication treatment groupExtended-release naltrexoneInitiation of treatmentOpioid use outcomesPrevalence of depressionRisk of relapseDeaths of despairInjection naltrexoneXR-NTXOpioid useDepression treatmentFrequent historyTreatment groupsPatientsLogistic regressionAnxiety disordersCannabis use among U.S. military veterans with subthreshold or threshold posttraumatic stress disorder: Psychiatric comorbidities, functioning, and strategies for coping with posttraumatic stress symptoms
Hill ML, Loflin M, Nichter B, Na PJ, Herzog S, Norman SB, Pietrzak RH. Cannabis use among U.S. military veterans with subthreshold or threshold posttraumatic stress disorder: Psychiatric comorbidities, functioning, and strategies for coping with posttraumatic stress symptoms. Journal Of Traumatic Stress 2022, 35: 1154-1166. PMID: 35275431, DOI: 10.1002/jts.22823.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalCannabisHumansStress Disorders, Post-TraumaticSuicidal IdeationVeteransConceptsU.S. military veteransFull PTSDCannabis usePTSD symptomsPosttraumatic stress disorder (PTSD) symptomsThreshold Posttraumatic Stress DisorderMilitary veteransPosttraumatic stress symptomsPosttraumatic stress disorderPsychiatric symptomsFrequent cannabis useMental health treatmentCurrent psychiatric symptomsCo-occurring depressionCognitive functioningBehavioral disengagementDisorder symptomsStress disorderStress symptomsFrequent cannabisTreatment engagementPTSDVeterans StudyHealth treatmentSubstance use
2021
Epidemiology of DSM-5 alcohol use disorder in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Panza KE, Kline AC, Na PJ, Potenza MN, Norman SB, Pietrzak RH. Epidemiology of DSM-5 alcohol use disorder in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Drug And Alcohol Dependence 2021, 231: 109240. PMID: 34974271, DOI: 10.1016/j.drugalcdep.2021.109240.Peer-Reviewed Original ResearchConceptsDSM-5 alcohol use disorderAlcohol use disorderPast-year alcohol use disorderLifetime alcohol use disorderAdverse childhood experiencesNational HealthUse disordersU.S. veteransVeterans StudySuicidal behaviorPrevalent public health concernPopulation-based burdenPrevalence of lifetimeSevere alcohol use disorderPublic health concernChildhood experiencesU.S. military veteransLifetime prevalenceLifetime PTSDPsychiatric characteristicsPsychiatric disordersDiagnostic criteriaElevated oddsVeteran populationPreventive effortsPsychosocial moderators of polygenic risk for suicidal ideation: Results from a 7-year population-based, prospective cohort study of U.S. veterans
Na PJ, De Angelis F, Nichter B, Wendt FR, Krystal JH, Southwick SM, Levey DF, Gelernter J, Polimanti R, Pietrzak RH. Psychosocial moderators of polygenic risk for suicidal ideation: Results from a 7-year population-based, prospective cohort study of U.S. veterans. Molecular Psychiatry 2021, 27: 1068-1074. PMID: 34725455, DOI: 10.1038/s41380-021-01352-2.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesGenome-Wide Association StudyHumansProspective StudiesSuicidal IdeationVeteransConceptsNew-onset suicidal ideationChronic suicidal ideationPolygenic risk scoresSuicidal ideationProspective cohort studyPolygenic riskRisk of SIHigher baseline levelsHigh polygenic riskModifiable psychosocial factorsSocial supportDispositional optimismCohort studyProspective cohortUS veteransSymptomatic courseRisk scorePsychosocial factorsGenome-wide association studiesBaseline levelsU.S. veteransSuicidal thoughtsPsychosocial moderatorsStudy periodLarge genome-wide association studiesPrevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic
Nichter B, Hill ML, Na PJ, Kline AC, Norman SB, Krystal JH, Southwick SM, Pietrzak RH. Prevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic. JAMA Psychiatry 2021, 78: 1218-1227. PMID: 34431973, PMCID: PMC8387942, DOI: 10.1001/jamapsychiatry.2021.2332.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCOVID-19FemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalenceRisk FactorsSuicidal IdeationUnited StatesVeteransConceptsUS military veteransCOVID-19 infectionCohort studySuicidal behaviorPast-year suicide ideationRisk factorsMilitary veteransPopulation-based prospective cohort studyCOVID-19 pandemicSuicide ideationSuicide attemptsProspective cohort studyLifetime posttraumatic stress disorderStrong risk factorCOVID-19 public health emergencyLow social supportPosttraumatic stress disorderPublic health emergencyAlcohol use disorder severityUS veteransNational HealthMAIN OUTCOMESuicide attempt historyVeterans StudyCOVID-19-related variablesSeverity of substance use as an indicator of suicide risk among U.S. military veterans
Na PJ, Nichter B, Hill ML, Kim B, Norman SB, Pietrzak RH. Severity of substance use as an indicator of suicide risk among U.S. military veterans. Addictive Behaviors 2021, 122: 107035. PMID: 34246987, DOI: 10.1016/j.addbeh.2021.107035.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismDepressive Disorder, MajorHumansRisk FactorsStress Disorders, Post-TraumaticSuicidal IdeationSuicideVeteransConceptsAlcohol Use Disorders Identification TestHigh-risk subsampleAlcohol use disorderPosttraumatic stress disorderPast-year suicidal ideationDrug use disordersMajor depressive disorderSevere alcohol use disorderUse disordersSuicide risk assessmentSuicidal ideationPast-year alcohol use disorderSubstance usePast-year drug use disordersStrong risk factorNon-prescription drugsCharacteristic curve analysisDisorders Identification TestU.S. military veteransDepressive disorderNational HealthRisk factorsClinical utilityElevated riskDrug useMental health and suicidal ideation in US military veterans with histories of COVID-19 infection
Na P, Tsai J, Harpaz-Rotem I, Pietrzak R. Mental health and suicidal ideation in US military veterans with histories of COVID-19 infection. BMJ Military Health 2021, 168: 15-19. PMID: 34035155, PMCID: PMC8154290, DOI: 10.1136/bmjmilitary-2021-001846.Peer-Reviewed Original ResearchMeSH KeywordsCOVID-19Depressive Disorder, MajorHumansMental HealthProspective StudiesSARS-CoV-2Suicidal IdeationVeteransConceptsStrong independent predictorUS military veteransSuicidal ideationIndependent predictorsCOVID-19COVID-related stressorsInternalising disordersPsychiatric conditionsProtective factorsMilitary veteransCOVID-19 infectionLogistic regression analysisPsychiatric symptom severityLower household incomeCurrent suicidal ideationSubstance use problemsProspective cohortMultivariable analysisTrauma burdenPositive screenUS veteransNational HealthPsychiatric symptomsPsychiatric disordersVeterans StudyPrevalence, risk and protective factors associated with suicidal ideation during the COVID-19 pandemic in U.S. military veterans with pre-existing psychiatric conditions
Na PJ, Tsai J, Hill ML, Nichter B, Norman SB, Southwick SM, Pietrzak RH. Prevalence, risk and protective factors associated with suicidal ideation during the COVID-19 pandemic in U.S. military veterans with pre-existing psychiatric conditions. Journal Of Psychiatric Research 2021, 137: 351-359. PMID: 33756377, PMCID: PMC8545743, DOI: 10.1016/j.jpsychires.2021.03.021.Peer-Reviewed Original ResearchConceptsPre-existing psychiatric conditionsPsychiatric symptom severitySuicidal ideationPsychiatric conditionsPsychiatric symptomsSymptom severityCOVID-19Protective factorsCoronavirus disease 2019 (COVID-19) pandemicPast-year suicidal ideationCOVID-19 infectionDisease 2019 pandemicLifetime suicide attemptsU.S. military veteransMultivariable analysisNational HealthOlder veteransGeneral populationRepresentative cohortU.S. veteransVeterans StudySuicide attemptsOlder ageSuicide riskPsychosocial difficulties
2018
The PHQ-9 Item 9 based screening for suicide risk: a validation study of the Patient Health Questionnaire (PHQ)−9 Item 9 with the Columbia Suicide Severity Rating Scale (C-SSRS)
Na PJ, Yaramala SR, Kim JA, Kim H, Goes FS, Zandi PP, Voort J, Sutor B, Croarkin P, Bobo WV. The PHQ-9 Item 9 based screening for suicide risk: a validation study of the Patient Health Questionnaire (PHQ)−9 Item 9 with the Columbia Suicide Severity Rating Scale (C-SSRS). Journal Of Affective Disorders 2018, 232: 34-40. PMID: 29477096, DOI: 10.1016/j.jad.2018.02.045.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedNeuropsychological TestsPregnancyReference StandardsRegistriesReproducibility of ResultsRisk AssessmentSensitivity and SpecificitySocioeconomic FactorsSuicidal IdeationSuicideSurveys and QuestionnairesYoung AdultConceptsPatient Health QuestionnaireColumbia-Suicide Severity Rating ScaleSeverity Rating ScaleSuicide riskItem 9Health QuestionnaireRating ScaleGold standardOverall poor resultsSuicide ideationClinical characteristicsOverall cohortCare registriesPHQ-9Depressed patientsClinical subgroupsSuicide itemPatientsPassive thoughtsSurrogate measureRiskPoor resultsFurther investigationIdeationAssessment tool
2017
The relative influence of individual risk factors for attempted suicide in patients with bipolar I versus bipolar II disorder
Bobo WV, Na PJ, Geske JR, McElroy SL, Frye MA, Biernacka JM. The relative influence of individual risk factors for attempted suicide in patients with bipolar I versus bipolar II disorder. Journal Of Affective Disorders 2017, 225: 489-494. PMID: 28865370, DOI: 10.1016/j.jad.2017.08.076.Peer-Reviewed Original ResearchConceptsBody mass indexLifetime suicide attemptsRisk factorsBD-IISuicide attemptsAcute psychiatric problemsSubstance use comorbiditiesStrong risk factorCross-sectional cohortPrevalence of lifetimeBD II patientsMayo Clinic Bipolar Disorder BiobankIndividual risk factorsRapid cyclingRisk of lifetimeEntire cohortIllness onsetMass indexClinical variablesFemale sexIllness coursePsychiatric hospitalizationSuicidal patientsPsychiatric problemsStandardized questionnaire
2016
Predictors of suicidal ideation in Korean American older adults: analysis of the Memory and Aging Study of Koreans (MASK)
Na PJ, Kim KB, Lee‐Tauler S, Han H, Kim MT, Lee HB. Predictors of suicidal ideation in Korean American older adults: analysis of the Memory and Aging Study of Koreans (MASK). International Journal Of Geriatric Psychiatry 2016, 32: 1272-1279. PMID: 27779333, PMCID: PMC5993045, DOI: 10.1002/gps.4608.Peer-Reviewed Original ResearchConceptsKorean American older adultsSelf-rated mental healthMinor depressive syndromeDepressive syndromeAmerican older adultsSuicidal ideationOlder adultsMental healthHealth statusPoor self-rated mental healthMajor depressive syndromePatient Health QuestionnairePhysical health statusMental health statusSuicide prevention interventionsCommunity-representative sampleHealth QuestionnaireEpidemiologic studiesPrevention interventionsSelf-rated mental health statusBaltimore-Washington areaSyndromeSuicide riskEarly detectionAging Study