2024
Problem Opioid Use Among US Military Veterans: Prevalence, Correlates, and Psychiatric Characteristics
Na P, Petrakis I, Krystal J, Pietrzak R. Problem Opioid Use Among US Military Veterans: Prevalence, Correlates, and Psychiatric Characteristics. Journal Of Addiction Medicine 2024, 18: 313-318. PMID: 38498625, PMCID: PMC11150085, DOI: 10.1097/adm.0000000000001286.Peer-Reviewed Original ResearchInstrumental activities of daily livingInstrumental activities of daily living disabilityLifetime suicide attemptsProblem opioid useUS military veteransUS veteransPsychiatric characteristicsSuicide attemptsMilitary veteransAssociated with black race/ethnicityActivities of daily livingNational Health and ResilienceLifetime alcohol use disorderMental health morbidityPosttraumatic stress disorderMental health disordersAlcohol use disorderNon-Hispanic race/ethnicityMultivariate logistic regression modelNationally representative sampleOpioid useLogistic regression modelsInstrumental activitiesHealth morbidityDaily living
2023
Purpose in life protects against the development of suicidal thoughts and behaviors in U.S. veterans without a history of suicidality: A 10-year, nationally representative, longitudinal study
Fischer I, Nichter B, Feldman D, Na P, Tsai J, Harpaz-Rotem I, Schulenberg S, Pietrzak R. Purpose in life protects against the development of suicidal thoughts and behaviors in U.S. veterans without a history of suicidality: A 10-year, nationally representative, longitudinal study. Journal Of Affective Disorders 2023, 340: 551-554. PMID: 37557988, DOI: 10.1016/j.jad.2023.08.040.Peer-Reviewed Original ResearchConceptsIncident suicidal ideationAlcohol use disorderIncident suicide attemptsCurrent alcohol use disorderHistory of STBSuicidal ideationSuicide attemptsBaseline predictorsDaily livingPopulation-based prospective cohort studySuicidal thoughtsLow purposeCurrent posttraumatic stress disorderProspective cohort studyTraditional risk factorsLower annual household incomeMultivariable regression analysisEvidence-based interventionsUS military veteransPosttraumatic stress disorderAnnual household incomeCohort studyTrauma burdenRisk factorsNational HealthLongitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic
Fischer I, Nichter B, Na P, Norman S, Krystal J, Pietrzak R. Longitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic. JAMA Psychiatry 2023, 80: 577-584. PMID: 37017978, PMCID: PMC10077136, DOI: 10.1001/jamapsychiatry.2023.0393.Peer-Reviewed Original ResearchConceptsNew-onset suicidal ideationUS military veteransLifetime substance use disorderPast-year suicidal ideationSubstance use disordersSuicidal ideationSuicide planningMilitary veteransUse disordersPsychiatric distressCOVID-19 pandemicSuicidal thoughtsPopulation-based longitudinal studyEvidence-based preventionLongitudinal studyLongitudinal trendsCohort studyNational HealthUS veteransMAIN OUTCOMEVeterans StudySuicide attemptsSuicide riskVulnerable populationsVeterans
2022
Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden
Nichter B, Koller D, De Angelis F, Wang J, Girgenti M, Na P, Hill M, Norman S, Krystal J, Gelernter J, Polimanti R, Pietrzak R. Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden. Psychological Medicine 2022, 53: 6325-6333. PMID: 36444557, DOI: 10.1017/s0033291722003646.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresUS military veteransLifetime suicide attemptsSuicide attemptsTrauma exposureTrauma burdenGenetic liabilityMilitary veteransDrug repurposing analysisPopulation-based sampleCumulative trauma exposureLifetime trauma exposureLow trauma exposureSuicide prediction modelsChronic inflammationInflammatory processNervous system developmentRisk scorePsychiatric characteristicsSuicidal behaviorExposure interactionsLarge genome-wide association studiesHigh levelsVeteransSuicidalityIdentifying factors associated with elevated suicidal intent among U.S. military veterans
Nichter B, Na PJ, Stanley IH, Marx BP, Herzog S, Moynahan V, Hill ML, Norman SB, Pietrzak RH. Identifying factors associated with elevated suicidal intent among U.S. military veterans. Journal Of Psychiatric Research 2022, 155: 68-74. PMID: 35988305, DOI: 10.1016/j.jpsychires.2022.08.001.Peer-Reviewed Original ResearchConceptsSuicidal intentU.S. military veteransHigh riskU.S. veteransPast-year suicidal ideationMilitary veteransPopulation-based sampleCurrent suicidal intentPrior suicide attemptsRisk factorsNational HealthCurrent insomniaCurrent depressionSuicidal ideationVeterans StudyVulnerability factorsSuicide attemptsSuicidal behaviorChildhood sexual abuseCo-occurring factorsSuicide mortalityVeterans' reportsSpecific vulnerability factorVeteransRepresentative sample“Lives of despair” at risk for “deaths of despair”: tracking an under-recognized, vulnerable population
Na PJ, Stefanovics EA, Rhee TG, Rosenheck RA. “Lives of despair” at risk for “deaths of despair”: tracking an under-recognized, vulnerable population. Social Psychiatry And Psychiatric Epidemiology 2022, 57: 1123-1134. PMID: 35028698, PMCID: PMC8757395, DOI: 10.1007/s00127-022-02218-w.Peer-Reviewed Original ResearchConceptsSubstance use disordersLifetime substance use disorderDeaths of despairSuicide attemptsUS adultsMental health service utilizationMental health care servicesQuality mental health careHealth service utilizationRelated Conditions Wave IIIMental health treatmentMental health careNational Epidemiologic SurveyQuality of lifeMore psychosocial adversityHealth care servicesCharacteristics of adultsMultivariable analysisService utilizationPsychiatric disordersUse disordersEpidemiologic SurveyWave IIIHealth treatmentAdverse experiences
2021
Prevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic
Nichter B, Hill ML, Na PJ, Kline AC, Norman SB, Krystal JH, Southwick SM, Pietrzak RH. Prevalence and Trends in Suicidal Behavior Among US Military Veterans During the COVID-19 Pandemic. JAMA Psychiatry 2021, 78: 1218-1227. PMID: 34431973, PMCID: PMC8387942, DOI: 10.1001/jamapsychiatry.2021.2332.Peer-Reviewed Original ResearchConceptsUS military veteransCOVID-19 infectionCohort studySuicidal behaviorPast-year suicide ideationRisk factorsMilitary veteransPopulation-based prospective cohort studyCOVID-19 pandemicSuicide ideationSuicide attemptsProspective cohort studyLifetime posttraumatic stress disorderStrong risk factorCOVID-19 public health emergencyLow social supportPosttraumatic stress disorderPublic health emergencyAlcohol use disorder severityUS veteransNational HealthMAIN OUTCOMESuicide attempt historyVeterans StudyCOVID-19-related variablesPrevalence, risk and protective factors associated with suicidal ideation during the COVID-19 pandemic in U.S. military veterans with pre-existing psychiatric conditions
Na PJ, Tsai J, Hill ML, Nichter B, Norman SB, Southwick SM, Pietrzak RH. Prevalence, risk and protective factors associated with suicidal ideation during the COVID-19 pandemic in U.S. military veterans with pre-existing psychiatric conditions. Journal Of Psychiatric Research 2021, 137: 351-359. PMID: 33756377, PMCID: PMC8545743, DOI: 10.1016/j.jpsychires.2021.03.021.Peer-Reviewed Original ResearchConceptsPre-existing psychiatric conditionsPsychiatric symptom severitySuicidal ideationPsychiatric conditionsPsychiatric symptomsSymptom severityCOVID-19Protective factorsCoronavirus disease 2019 (COVID-19) pandemicPast-year suicidal ideationCOVID-19 infectionDisease 2019 pandemicLifetime suicide attemptsU.S. military veteransMultivariable analysisNational HealthOlder veteransGeneral populationRepresentative cohortU.S. veteransVeterans StudySuicide attemptsOlder ageSuicide riskPsychosocial difficulties
2017
The relative influence of individual risk factors for attempted suicide in patients with bipolar I versus bipolar II disorder
Bobo WV, Na PJ, Geske JR, McElroy SL, Frye MA, Biernacka JM. The relative influence of individual risk factors for attempted suicide in patients with bipolar I versus bipolar II disorder. Journal Of Affective Disorders 2017, 225: 489-494. PMID: 28865370, DOI: 10.1016/j.jad.2017.08.076.Peer-Reviewed Original ResearchConceptsBody mass indexLifetime suicide attemptsRisk factorsBD-IISuicide attemptsAcute psychiatric problemsSubstance use comorbiditiesStrong risk factorCross-sectional cohortPrevalence of lifetimeBD II patientsMayo Clinic Bipolar Disorder BiobankIndividual risk factorsRapid cyclingRisk of lifetimeEntire cohortIllness onsetMass indexClinical variablesFemale sexIllness coursePsychiatric hospitalizationSuicidal patientsPsychiatric problemsStandardized questionnaire