2006
Genomic aberrations are rare in urothelial neoplasms of patients 19 years or younger
Wild P, Giedl J, Stoehr R, Junker K, Boehm S, van Oers J, Zwarthoff E, Blaszyk H, Fine S, Humphrey P, Dehner L, Amin M, Epstein J, Hartmann A. Genomic aberrations are rare in urothelial neoplasms of patients 19 years or younger. The Journal Of Pathology 2006, 211: 18-25. PMID: 17072825, DOI: 10.1002/path.2075.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlphapapillomavirusChildChild, PreschoolChromosome AberrationsChromosomes, Human, Pair 9DNA Mismatch RepairDNA Mutational AnalysisDNA, ViralFemaleGene Expression ProfilingGenes, p53HumansImmunohistochemistryIn Situ Hybridization, FluorescenceLoss of HeterozygosityMaleMicrosatellite InstabilityOligonucleotide Array Sequence AnalysisPapillomaPolymerase Chain ReactionReceptor, Fibroblast Growth Factor, Type 3Urologic NeoplasmsUrotheliumConceptsPatients 19 yearsUrothelial neoplasmsUrothelial papillomaMicrosatellite instabilityClinical outcomesHuman papillomavirusTP53 mutationsHigh-grade papillary urothelial carcinomaNIH consensus panelEvidence of diseaseFavorable clinical outcomeLow malignant potentialChromosome arm 9pPapillary urothelial carcinomaComparative genomic hybridizationPapillary urothelial neoplasmHPV positivityYounger patientsMultifocal tumorsUrothelial carcinomaUrothelial tumorsMalignant potentialPolymerase chain reactionConsensus panelKi-67
2000
Squamous Cell Carcinoma Arising in Recurrent Respiratory Papillomatosis with Pulmonary Involvement: Emerging Common Pattern of Clinical Features and Human Papillomavirus Serotype Association
Cook J, Hill D, Humphrey P, Pfeifer J, El-Mofty S. Squamous Cell Carcinoma Arising in Recurrent Respiratory Papillomatosis with Pulmonary Involvement: Emerging Common Pattern of Clinical Features and Human Papillomavirus Serotype Association. Modern Pathology 2000, 13: 914-918. PMID: 10955460, DOI: 10.1038/modpathol.3880164.Peer-Reviewed Original ResearchConceptsRecurrent respiratory papillomatosisSquamous cell carcinomaJuvenile-onset recurrent respiratory papillomatosisRespiratory papillomatosisCell carcinomaClinical featuresInvasive carcinomaHPV-11Malignant transformationFatal squamous cell carcinomaHuman papillomavirus typingHPV 11 DNASimilar clinical featuresYoung adult menPulmonary papillomaPulmonary involvementSquamous papillomaHPV typingBenign papillomasPapillomatosisSerotype associationCarcinomaAdult menPapillomasLung
1992
Prevalence of human papillomavirus types 16 and 18 in squamous‐cell carcinoma of the penis: A retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction
Wiener J, Effert P, Humphrey P, Yu L, Liu E, Walther P. Prevalence of human papillomavirus types 16 and 18 in squamous‐cell carcinoma of the penis: A retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction. International Journal Of Cancer 1992, 50: 694-701. PMID: 1312062, DOI: 10.1002/ijc.2910500505.Peer-Reviewed Original ResearchConceptsHPV types 16Squamous cell carcinomaHPV 16Human papillomavirusType 16Metastatic sitesDifferential polymerase chain reactionHPV DNAMetastatic depositsHPV-18Polymerase chain reactionRetrospective analysisPresence of HPVType-specific HPV DNASeparate metastatic sitesCause-specific survivalHPV-negative groupKaplan-Meier analysisTumor histologic gradeHuman papillomavirus type 16Chain reactionPapillomavirus type 16Nodal involvementPatient ageHPV types