1993
Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias
Kohler M, Nishii H, Humphrey P, Saski H, Marks J, Bast R, Clarke-Pearson D, Boyd J, Berchuck A. Mutation of the p53 tumor-suppressor gene is not a feature of endometrial hyperplasias. American Journal Of Obstetrics And Gynecology 1993, 169: 690-694. PMID: 8372881, DOI: 10.1016/0002-9378(93)90644-x.Peer-Reviewed Original Research
1992
Prevalence of human papillomavirus types 16 and 18 in squamous‐cell carcinoma of the penis: A retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction
Wiener J, Effert P, Humphrey P, Yu L, Liu E, Walther P. Prevalence of human papillomavirus types 16 and 18 in squamous‐cell carcinoma of the penis: A retrospective analysis of primary and metastatic lesions by differential polymerase chain reaction. International Journal Of Cancer 1992, 50: 694-701. PMID: 1312062, DOI: 10.1002/ijc.2910500505.Peer-Reviewed Original ResearchConceptsHPV types 16Squamous cell carcinomaHPV 16Human papillomavirusType 16Metastatic sitesDifferential polymerase chain reactionHPV DNAMetastatic depositsHPV-18Polymerase chain reactionRetrospective analysisPresence of HPVType-specific HPV DNASeparate metastatic sitesCause-specific survivalHPV-negative groupKaplan-Meier analysisTumor histologic gradeHuman papillomavirus type 16Chain reactionPapillomavirus type 16Nodal involvementPatient ageHPV types
1991
Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function
Humphrey P, Gangarosa L, Wong A, Archer G, Lund-Johansen M, Bjerkvig R, Laerum O, Friedman H, Bigner D. Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function. Biochemical And Biophysical Research Communications 1991, 178: 1413-1420. PMID: 1678600, DOI: 10.1016/0006-291x(91)91051-d.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCell LineChromosome DeletionEpidermal Growth FactorErbB ReceptorsGene AmplificationGene RearrangementGliomaHumansKineticsMolecular Sequence DataPhosphorylationProtein-Tyrosine KinasesProto-Oncogene MasProto-Oncogene ProteinsProto-OncogenesReceptor, ErbB-2Transforming Growth Factor alphaConceptsEGFR kinase activityMutant EGFRDeletion-mutant epidermal growth factor receptorGrowth factor receptor geneMutant EGFR proteinEpidermal growth factor receptorGrowth factorFactor receptor geneEpidermal growth factor receptor (EGFR) geneGrowth factor receptorKinase activityExtracellular domainGlioma cell proliferationDomain IVFrame deletionType II mutationAmino acidsEGFR proteinFactor receptorReceptor geneThree-dimensional spheroid modelCell proliferationReceptor functionEGFHuman gliomas