1998
Predicting the pathology results of radical prostatectomy from preoperative information
Vollmer R, Keetch D, Humphrey P. Predicting the pathology results of radical prostatectomy from preoperative information. Cancer 1998, 83: 1567-1580. PMID: 9781951, DOI: 10.1002/(sici)1097-0142(19981015)83:8<1567::aid-cncr12>3.0.co;2-e.Peer-Reviewed Original ResearchConceptsRadical prostatectomyPreoperative informationNeedle biopsyTumor volumeStatistical methodsWashington University Medical CenterAdvanced tumor stageProstate-specific antigenUniversity Medical CenterPreoperative variablesSerum PSATumor stagePathology resultsPathology outcomesMedical CenterProstate carcinomaSpecific antigenProstatectomyLogistic regressionBinary outcomesMultivariate modelProbabilityOutcomesBiopsyObserved probability
1996
Prospective characterization of pathological features of Prostatic Carcinomas Detected Via Serum Prostate Specific Antigen Based Screening
Humphrey P, Keetch D, Smith D, Shepherd D, Catalona W. Prospective characterization of pathological features of Prostatic Carcinomas Detected Via Serum Prostate Specific Antigen Based Screening. Journal Of Urology 1996, 155: 816-820.. DOI: 10.1097/00005392-199603000-00004.Peer-Reviewed Original ResearchProstate-specific antigenSerum prostate-specific antigenPathological featuresProstatic carcinomaSpecific antigenOrgan-confined prostate carcinomaCancerous surgical marginsGleason histological gradeIntraglandular tumor extentMost prostatic cancersMost prostatic carcinomasSurgical margin statusRadical prostatectomy specimensExtracapsular carcinomaAdvanced diseaseMargin statusSurgical marginsGleason scoreHistological gradePathological stageSurgical specimenProspective dataProstatic cancerTumor extentProspective characterizationProspective characterization of pathological features of Prostatic Carcinomas Detected Via Serum Prostate Specific Antigen Based Screening
Humphrey P, Keetch D, Smith D, Shepherd D, Catalona W. Prospective characterization of pathological features of Prostatic Carcinomas Detected Via Serum Prostate Specific Antigen Based Screening. Journal Of Urology 1996, 155: 816-820. PMID: 8583583, DOI: 10.1016/s0022-5347(01)66316-x.Peer-Reviewed Original ResearchConceptsProstate-specific antigenSerum prostate-specific antigenPathological featuresProstatic carcinomaSpecific antigenOrgan-confined prostate carcinomaCancerous surgical marginsGleason histological gradeIntraglandular tumor extentMost prostatic cancersMost prostatic carcinomasSurgical margin statusRadical prostatectomy specimensExtracapsular carcinomaAdvanced diseaseMargin statusSurgical marginsGleason scoreHistological gradePathological stageSurgical specimenProspective dataProstatic cancerTumor extentProspective characterization
1995
Relationship between serum prostate specific antigen, needle biopsy findings, and histopathologic features of prostatic carcinoma in radical prostatectomy tissues
Humphrey P, Baty J, Keetch D. Relationship between serum prostate specific antigen, needle biopsy findings, and histopathologic features of prostatic carcinoma in radical prostatectomy tissues. Cancer 1995, 75: 1842-1849. DOI: 10.1002/1097-0142(19950401)75:7+<1842::aid-cncr2820751614>3.0.co;2-2.Peer-Reviewed Original ResearchSerum prostate-specific antigenProstate-specific antigenPSA densityNeedle biopsy findingsPositive biopsy resultsHistologic gradeNeedle biopsyBiopsy findingsHistopathologic featuresTumor sizeBiopsy resultsProstate cancerPretreatment serum prostate-specific antigenSpecific antigenWhole glandAggressive prostate cancerPercentage of carcinomaRadical prostatectomy specimensRadical prostatectomy tissueWhole prostate glandBiopsy featuresPathologic stageDifferentiated tumorsProstatic carcinomaTumor grade
1993
Is Prostate Specific Antigen of Clinical Importance in Evaluating Outcome after Radical Prostatectomy
Frazier H, Robertson J, Humphrey P, Paulson D. Is Prostate Specific Antigen of Clinical Importance in Evaluating Outcome after Radical Prostatectomy. Journal Of Urology 1993, 149: 516-518. PMID: 7679755, DOI: 10.1016/s0022-5347(17)36132-3.Peer-Reviewed Original ResearchConceptsProstate-specific antigenPostoperative serum PSA levelsSerum PSA levelsPSA levelsPSA elevationSpecific antigenPostoperative prostate-specific antigenSerum prostate-specific antigenPostoperative PSA levelMargin-positive diseaseRadical perineal prostatectomySerum acid phosphatasePositive diseaseBone scanCurative therapyLocal recurrenceTreatment courseRadical prostatectomyMalignant diseasePerineal prostatectomyClinical failureProstate cancerPositive groupPatientsClinical importance
1992
Immunoreactive Prostatic Specific Antigen in Male Periurethral Glands
Frazier H, Humphrey P, Burchette J, Paulson D. Immunoreactive Prostatic Specific Antigen in Male Periurethral Glands. Journal Of Urology 1992, 147: 246-248. PMID: 1370330, DOI: 10.1016/s0022-5347(17)37206-3.Peer-Reviewed Original ResearchConceptsProstatic specific antigenProstatic acid phosphatasePeriurethral glandsSpecific antigenUrethral specimensMalignant prostatic tissueMale urethral specimensAutopsy seriesUrethral biopsyProstatic cancerAntigen uniqueAutopsy specimensProstatic tissueStrong immunostainingHeterogenous stainingAntigenAcid phosphataseRecent evidenceGlandTissueBiopsyEvidencePatientsCancerImmunostaining