2001
The Relative Importance of Anatomic and PSA Factors to Outcomes After Radical Prostatectomy for Prostate Cancer
Vollmer R, Humphrey P. The Relative Importance of Anatomic and PSA Factors to Outcomes After Radical Prostatectomy for Prostate Cancer. American Journal Of Clinical Pathology 2001, 116: 864-870. PMID: 11764075, DOI: 10.1309/7mq7-mwar-4w8a-r75f.Peer-Reviewed Original ResearchConceptsElevated PSA levelsEarly deathPSA levelsRadical prostatectomyProstate cancerPathology observationsGleason grade 5Overall good prognosisTime of prostatectomyPostoperative levelsPSA failureStudy patientsBetter prognosisProgressive tumorsPrognostic categoriesPercentage carcinomaProstatectomySubsequent outcomesLower hazardDeathSurgeryHigher hazardCancerMenPSA
1998
THE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER
ORNSTEIN D, SMITH D, HUMPHREY P, CATALONA W. THE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER. Journal Of Urology 1998, 159: 1234-1237.. DOI: 10.1097/00005392-199804000-00043.Peer-Reviewed Original ResearchProstate-specific antigen levelTotal PSA levelsSpecific antigen levelsDetectable prostate cancerSerum prostate-specific antigen levelFree PSA levelsPercent free PSAPSA levelsProstate volumeAcute inflammationAntigen levelsProstate cancerFree PSAFree Serum Prostate Specific Antigen LevelsTotal serum prostate-specific antigen (PSA) levelsTotal prostate-specific antigen levelsFree serum PSA levelsMean percent free PSAPercent free PSA levelsProstate cancer screening programsFree serum PSASerum PSA levelsLarge prostate glandsCancer screening programsInfluence of ageTHE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER
ORNSTEIN D, SMITH D, HUMPHREY P, CATALONA W. THE EFFECT OF PROSTATE VOLUME, AGE, TOTAL PROSTATE SPECIFIC ANTIGEN LEVEL AND ACUTE INFLAMMATION ON THE PERCENTAGE OF FREE SERUM PROSTATE SPECIFIC ANTIGEN LEVELS IN MEN WITHOUT CLINICALLY DETECTABLE PROSTATE CANCER. Journal Of Urology 1998, 159: 1234-1237. PMID: 9507843, DOI: 10.1016/s0022-5347(01)63570-5.Peer-Reviewed Original ResearchConceptsProstate-specific antigen levelTotal PSA levelsSpecific antigen levelsDetectable prostate cancerSerum prostate-specific antigen levelFree PSA levelsPercent free PSAPSA levelsProstate volumeAcute inflammationAntigen levelsProstate cancerFree PSAFree Serum Prostate Specific Antigen LevelsTotal serum prostate-specific antigen (PSA) levelsTotal prostate-specific antigen levelsFree serum PSA levelsMean percent free PSAPercent free PSA levelsProstate cancer screening programsFree serum PSASerum PSA levelsLarge prostate glandsCancer screening programsInfluence of age
1997
The early detection of prostate carcinoma with prostate specific antigen
Smith D, Humphrey P, Catalona W. The early detection of prostate carcinoma with prostate specific antigen. Cancer 1997, 80: 1852-1856. PMID: 9351559, DOI: 10.1002/(sici)1097-0142(19971101)80:9<1852::aid-cncr25>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsDigital rectal examinationSubset of menPositive predictive valueSignificant carcinomaPSA levelsRectal examinationProstate carcinomaPredictive valueScreening testDigital rectal examination resultsIntermediate outcomesCarcinoma detection rateEarly prostate carcinomaScreen-detected carcinomasScreen-detected tumorsInitial PSA levelReasonable positive predictive valueMajority of tumorsProstate-specific antigenProportion of menPathologic characteristicsClinicopathologic featuresPathologic featuresProstatic biopsyDisease stage
1993
Is Prostate Specific Antigen of Clinical Importance in Evaluating Outcome after Radical Prostatectomy
Frazier H, Robertson J, Humphrey P, Paulson D. Is Prostate Specific Antigen of Clinical Importance in Evaluating Outcome after Radical Prostatectomy. Journal Of Urology 1993, 149: 516-518. PMID: 7679755, DOI: 10.1016/s0022-5347(17)36132-3.Peer-Reviewed Original ResearchConceptsProstate-specific antigenPostoperative serum PSA levelsSerum PSA levelsPSA levelsPSA elevationSpecific antigenPostoperative prostate-specific antigenSerum prostate-specific antigenPostoperative PSA levelMargin-positive diseaseRadical perineal prostatectomySerum acid phosphatasePositive diseaseBone scanCurative therapyLocal recurrenceTreatment courseRadical prostatectomyMalignant diseasePerineal prostatectomyClinical failureProstate cancerPositive groupPatientsClinical importanceStratification of pathologic features in radical prostatectomy specimens that are predictive of elevated initial postoperative serum prostate‐specific antigen levels
Humphrey P, Frazier H, Vollmer R, Paulson D. Stratification of pathologic features in radical prostatectomy specimens that are predictive of elevated initial postoperative serum prostate‐specific antigen levels. Cancer 1993, 71: 1821-1827. PMID: 7680602, DOI: 10.1002/1097-0142(19930301)71:5<1821::aid-cncr2820710517>3.0.co;2-o.Peer-Reviewed Original ResearchConceptsPostoperative PSA levelPostoperative serum PSA levelsSerum PSA levelsRadical prostatectomy specimensIntraglandular tumor extentPSA levelsPathologic stageMargin positivityProstate-specific antigenHistologic gradeProstatectomy specimensResidual carcinomaPathologic featuresTumor extentSerum prostate-specific antigen levelPercentage carcinomaProstate-specific antigen levelExtension of carcinomaGleason histologic gradeOrgan-confined carcinomaLogistic regression analysisImportant morphologic parametersIntraglandular carcinomaAntigen levelsRadical prostatectomy