2006
Immunohistochemistry in the diagnosis of minimal prostate cancer
Hameed O, Humphrey P. Immunohistochemistry in the diagnosis of minimal prostate cancer. Diagnostic Histopathology 2006, 12: 279-291. DOI: 10.1016/j.cdip.2006.05.003.Peer-Reviewed Original ResearchBasal cell markersProstatic adenocarcinomaProstate needle biopsy tissueCell markersMinimal prostate cancerNeedle biopsy tissueEosin-stained sectionsCytokeratin 5/6Invasive carcinomaProstatic lesionsProstate cancerDiagnostic yieldBenign mimickersBiopsy tissueImmunohistochemistryConcurrent useAdenocarcinomaDiagnosisBasal cellsAntibodiesMarkers
2000
Minimal Adenocarcinoma in Prostate Needle Biopsy Tissue
Thorson P, Humphrey P. Minimal Adenocarcinoma in Prostate Needle Biopsy Tissue. American Journal Of Clinical Pathology 2000, 114: 896-909. PMID: 11338479, DOI: 10.1309/kvpx-c1em-142l-1m6w.Peer-Reviewed Original ResearchConceptsNeedle biopsy tissueProstate needle biopsy tissueMinor diagnostic criteriaBiopsy tissueProstatic adenocarcinomaDiagnostic criteriaMinimal adenocarcinomaHigh-grade prostatic intraepithelial neoplasiaAtypical small acinar proliferationFocal glandular atypiaValuable adjunctive studySmall acinar proliferationProstatic intraepithelial neoplasiaAtypical adenomatous hyperplasiaConstellation of findingsIntermediate histologic gradeMajor diagnostic challengeWhole prostate gland
1998
Diagnostic Effect of Complete Histologic Sampling of Prostate Needle Biopsy Specimens
Reyes A, Humphrey P. Diagnostic Effect of Complete Histologic Sampling of Prostate Needle Biopsy Specimens. American Journal Of Clinical Pathology 1998, 109: 416-422. PMID: 9535395, DOI: 10.1093/ajcp/109.4.416.Peer-Reviewed Original ResearchConceptsHigh-grade PINProstate needle biopsy specimensFocal glandular atypiaNeedle biopsy tissueNeedle biopsy specimensBenign prostatic tissueAdditional slidesHistologic abnormalitiesBiopsy specimensGlandular atypiaHistologic samplingNeedle biopsyProstatic tissueBiopsy tissueProstate needle core biopsiesNeedle core biopsyProstate needle biopsyComplete histopathologic examinationDetection of carcinomaDiagnostic effectComplete histologic examinationAdditional histologicProspective studyDefinitive diagnosisHistopathologic examination