2024
Efficacy and safety of implantable cardioverter-defibrillator implantation in the elderly—The I-70 Study: A randomized clinical trial
Singh S, Wininger M, Raitt M, Adabag S, Moore H, Rottman J, Scrymgeour A, Zhang J, Zheng K, Guarino P, Kyriakides T, Group I, Johnson G, Williams A, Beed A, MacMurdy K, Saavedra P. Efficacy and safety of implantable cardioverter-defibrillator implantation in the elderly—The I-70 Study: A randomized clinical trial. Heart Rhythm O2 2024, 5: 365-373. PMID: 38984364, PMCID: PMC11228113, DOI: 10.1016/j.hroo.2024.04.010.Peer-Reviewed Original ResearchImplantable cardioverter defibrillatorParticipant follow-upPatient treatment preferencesICD implantationFollow-upTarget sample sizeAll-cause hospitalizationsPrimary prevention ICD implantationMonths of follow-upImplantable cardioverter defibrillator therapySafety of implantable cardioverter defibrillatorsImplantable cardioverter defibrillator implantationOptimal medical therapyRate of sudden deathTreatment preferencesImplantable cardioverter defibrillator shocksSafety of ICD implantationConfidence intervalsStudy protocolMedical therapyParticipantsProlonging lifePatientsSudden deathCardioverter defibrillator
2006
A brief measure of perceived understanding of informed consent in a clinical trial was validated
Guarino P, Lamping DL, Elbourne D, Carpenter J, Peduzzi P. A brief measure of perceived understanding of informed consent in a clinical trial was validated. Journal Of Clinical Epidemiology 2006, 59: 608-614. PMID: 16713523, DOI: 10.1016/j.jclinepi.2005.11.009.Peer-Reviewed Original ResearchConceptsInformed Consent QuestionnaireClinical trialsGulf War veterans' illnessesPsychometric evaluationRandomized clinical trialsItem reduction techniquesVeterans AffairsItem reductionTrialsMonthsPoor acceptabilityFour-item subscaleValidity sampleIllnessGood acceptabilityInternal consistencyConsentBaselineSelf-report measuresBrief measureAcceptabilityParticipantsHospitalFollow