1987
Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line.
Lacy J, Summers W, Watson M, Glazer P, Summers W. Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 5838-5842. PMID: 3039510, PMCID: PMC298958, DOI: 10.1073/pnas.84.16.5838.Peer-Reviewed Original ResearchConceptsBurkitt's lymphomaEBV infectionB cell linesEpstein-Barr virus infectionEBV-negative Burkitt lymphomasEBV-positive sublinesEpstein-Barr virusAmplification of MYCRole of EBVMYC expressionPositive Burkitt's lymphomaHuman B cell linesDeregulation of MYCVirus infectionVitro infectionInfectionEBVAltered expressionBJAB cellsMYC transcriptionVirusMYC oncogeneMYC locusMYCCells
1985
Oncogene Expression in Isogenic, EBV-Positive and -Negative Burkitt Lymphoma Cell Lines
Glazer P, Summers W. Oncogene Expression in Isogenic, EBV-Positive and -Negative Burkitt Lymphoma Cell Lines. Intervirology 1985, 23: 82-89. PMID: 2984143, DOI: 10.1159/000149589.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusNegative Burkitt lymphoma cell lineCell linesBJAB cellsOncogene expressionC-MycBurkitt's lymphoma cell linesMechanism of actionEBV infectionBL cell linesEBV-positiveC-myc expressionLymphoma cell linesLymphoid cellsOncogene c-mycBL cellsElevated expressionNormal karyotypeInitial reportMode of actionChromosomal translocationsBJABChromosome 8Ha-rasCellular oncogenes