1999
The Tyr-265-to-Cys mutator mutant of DNA polymerase β induces a mutator phenotype in mouse LN12 cells
Clairmont C, Narayanan L, Sun K, Glazer P, Sweasy J. The Tyr-265-to-Cys mutator mutant of DNA polymerase β induces a mutator phenotype in mouse LN12 cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 9580-9585. PMID: 10449735, PMCID: PMC22251, DOI: 10.1073/pnas.96.17.9580.Peer-Reviewed Original ResearchConceptsMutator mutantsDNA polymerase betaTyr-265Mutator phenotypePolymerase betaWild-type DNA polymerase betaWild-type DNA polymeraseWild-type proteinBase excision repairRat DNA polymerase betaSpontaneous mutation frequencyDNA polymerase βDNA polymerase IMammalian cellsMutator polymeraseComplementation systemBeta mutantsExcision repairPolymerase IMutantsMutator activityGenetic instabilityHuman cellsPolymerase βEscherichia coli
1981
Initiation of Aggregation by Dictyostelium discoideum in Mutant Populations Lacking Pulsatile Signalling
GLAZER P, NEWELL P. Initiation of Aggregation by Dictyostelium discoideum in Mutant Populations Lacking Pulsatile Signalling. Microbiology 1981, 125: 221-232. DOI: 10.1099/00221287-125-2-221.Peer-Reviewed Original ResearchDictyostelium discoideumAggregation centersCell surface cyclic AMP receptorsAggregation-deficient mutantsContact site AWild-type cellsCyclic AMP receptorsWild-type strainCyclic AMP signalsWild-type amoebaeWild-type populationAmoebal populationsCyclic AMP pulsesActive adenylate cyclaseAMP receptorsCyclic AMPAMP signalsMutantsAggregation signalsAMP pulsesInitiation of aggregationDiscoideumPulsatile regulationCell adhesiveMixed population