2020
Assessment of Plasma Oxalate Concentration in Patients With CKD
Pfau A, Wytopil M, Chauhan K, Reichel M, Coca SG, Aronson PS, Eckardt KU, Knauf F. Assessment of Plasma Oxalate Concentration in Patients With CKD. Kidney International Reports 2020, 5: 2013-2020. PMID: 33163722, PMCID: PMC7609998, DOI: 10.1016/j.ekir.2020.08.029.Peer-Reviewed Original ResearchChronic kidney diseasePlasma oxalate concentrationGerman Chronic Kidney Disease (GCKD) studyChronic Kidney Disease studyObservational cohort studyGlomerular filtration rateLarge patient cohortKidney Disease studyKidney stone diseaseCKD progressionMedian eGFROngoing multicenterCohort studyKidney diseasePatient cohortPresent studyFiltration rateClinical trialsStone diseaseLarge cohortOxalate homeostasisPatientsDisease StudyPlasma samplesMaintenance of samples
2007
Ontogeny of NHE8 in the rat proximal tubule
Becker AM, Zhang J, Goyal S, Dwarakanath V, Aronson PS, Moe OW, Baum M. Ontogeny of NHE8 in the rat proximal tubule. American Journal Of Physiology. Renal Physiology 2007, 293: f255-f261. PMID: 17429030, PMCID: PMC4119019, DOI: 10.1152/ajprenal.00400.2006.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, WesternDNA, ComplementaryElectrophoresis, Polyacrylamide GelFemaleImmunohistochemistryKidney Tubules, ProximalMicroscopy, FluorescenceMicrovilliPregnancyProteinsRatsRats, Sprague-DawleyReverse Transcriptase Polymerase Chain ReactionRNASodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersConceptsRat proximal tubuleProximal tubulesAdult ratsNHE3 expressionProximal tubule bicarbonate reabsorptionReal-time RT-PCRProton secretionNeonatal proximal tubuleNHE8 expressionApical membraneBicarbonate reabsorptionMaturational increaseMaturational changesNeonatesNHE8RT-PCRBrush border membrane vesiclesTubulesRatsCortical membrane proteinsSecretionPresent studyDevelopmental expressionAdultsBorder membrane vesicles
2002
Formate-stimulated NaCl absorption in the proximal tubule is independent of the pendrin protein
Karniski LP, Wang T, Everett LA, Green ED, Giebisch G, Aronson PS. Formate-stimulated NaCl absorption in the proximal tubule is independent of the pendrin protein. American Journal Of Physiology. Renal Physiology 2002, 283: f952-f956. PMID: 12372770, DOI: 10.1152/ajprenal.00182.2002.Peer-Reviewed Original ResearchConceptsProximal tubulesChloride/formate exchangeNaCl reabsorptionChloride reabsorptionElectroneutral NaCl reabsorptionNaCl absorptionRole of pendrinFormate exchangePds-knockout mouseRecycling of formatePendrin proteinReabsorptionMicePendrinBrush border membrane vesiclesTubulesPresent studyChloride transportApical membraneSpecificity of Anion Exchange Mediated by Mouse Slc26a6*
Jiang Z, Grichtchenko II, Boron WF, Aronson PS. Specificity of Anion Exchange Mediated by Mouse Slc26a6*. Journal Of Biological Chemistry 2002, 277: 33963-33967. PMID: 12119287, DOI: 10.1074/jbc.m202660200.Peer-Reviewed Original ResearchConceptsProximal tubule cellsP-aminohippurateTubule cellsOxalate-sulfate exchangeTransport of oxalatePH recordingRenal tubular fluidTubular fluidVoltage-clamp measurementsBrush border membraneFormate exchangeOxalate exchangeMeasurement of uptakeClamp measurementsBorder membraneSlc26a6Two-electrode voltage clamp measurementsXenopus oocytesPresent studyHigh oxalate concentrationsApical membraneOocytesMouse orthologueCellsCFEX
1983
Urate transport via anion exchange in dog renal microvillus membrane vesicles
Kahn AM, Aronson PS. Urate transport via anion exchange in dog renal microvillus membrane vesicles. American Journal Of Physiology 1983, 244: f56-f63. PMID: 6849384, DOI: 10.1152/ajprenal.1983.244.1.f56.Peer-Reviewed Original ResearchConceptsDose-response curveP-aminohippurateUrate transportRenal microvillus membrane vesiclesUptake of PAHDog renal cortexMicrovillus membrane vesiclesAnion reabsorptionRenal cortexProximal tubulesTransport of urateUrateBrush border membrane vesiclesMembrane vesiclesUrate uptakePAH uptakeExternal ClPresent studyBorder membrane vesicles