2006
The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates
Knauf F, Mohebbi N, Teichert C, Herold D, Rogina B, Helfand S, Gollasch M, Luft FC, Aronson PS. The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. Biochemical Journal 2006, 397: 25-29. PMID: 16608441, PMCID: PMC1479758, DOI: 10.1042/bj20060409.Peer-Reviewed Original ResearchConceptsExternal citrateKrebs cycle intermediatesXenopus oocytesSodium dicarboxylate cotransporterMammalian genesDrosophila melanogasterIndy mutantsLifespan extensionLongevity genesPlasma membraneSubstrate effluxExternal mediumSpecific transport mechanismsFunctional studiesSuccinate uptakeAddition of succinateEnergy metabolismIndyTransportable substratesGenesOocytesEffluxMelanogasterMutantsSuccinate
1981
Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles
Kinsella JL, Aronson PS. Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles. American Journal Of Physiology 1981, 241: f374-f379. PMID: 7315961, DOI: 10.1152/ajprenal.1981.241.4.f374.Peer-Reviewed Original Research