Nav1.7 is the Predominant Sodium Channel in Rodent Olfactory Sensory Neurons
Ahn HS, Black JA, Zhao P, Tyrrell L, Waxman SG, Dib-Hajj SD. Nav1.7 is the Predominant Sodium Channel in Rodent Olfactory Sensory Neurons. Molecular Pain 2011, 7: 1744-8069-7-32. PMID: 21569247, PMCID: PMC3101130, DOI: 10.1186/1744-8069-7-32.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGanglia, SpinalGene Expression RegulationIn Situ HybridizationIon Channel GatingMaleMiceMice, Inbred C57BLNAV1.6 Voltage-Gated Sodium ChannelNAV1.7 Voltage-Gated Sodium ChannelOlfactory MucosaOlfactory Receptor NeuronsPolymerase Chain ReactionRatsRats, Sprague-DawleyRNA, MessengerSodium ChannelsConceptsDorsal root gangliaOlfactory sensory neuronsSodium channelsSensory neuronsNervous systemSodium channel transcriptsVoltage-gated sodium channel Nav1.7Peripheral nervous systemCentral nervous systemCompound heterozygous lossSodium channel Nav1.7Channel transcriptsPeripheral olfactory sensory neuronsCongenital insensitivityRoot gangliaSympathetic neuronsOSN axonsOlfactory bulbPostsynaptic cellOlfactory epitheliumChannel Nav1.7Nav1.7Nav1.6 channelsNull miceAnosmia