2024
Novel FOXL2 Mutation in an Ovarian Adult Granulosa Cell Tumor: Report of a Case With Diagnostic and Clinicopathologic Implications
Nagy A, Niu N, Ratner E, Hui P, Buza N. Novel FOXL2 Mutation in an Ovarian Adult Granulosa Cell Tumor: Report of a Case With Diagnostic and Clinicopathologic Implications. International Journal Of Gynecological Pathology 2024, 43: 631-636. PMID: 38426544, DOI: 10.1097/pgp.0000000000001024.Peer-Reviewed Original ResearchAdult granulosa cell tumorGranulosa cell tumorsOvarian sex cord-stromal tumorsSex cord-stromal tumorsCord-stromal tumorsCell tumorsFOXL2 mutationMutation c.Fibromatous stromaMalignant ovarian sex cord-stromal tumorAdjuvant vaginal cuff brachytherapyOvarian adult granulosa cell tumorsBilateral salpingo-oophorectomyRight ovarian massVaginal cuff brachytherapyAtypical endometrial hyperplasiaSuperficial myometrial invasionRoutine molecular testingUniform tumor cellsEndometrioid endometrial adenocarcinomaNested growth patternPoint mutation c.Months follow-upSalpingo-oophorectomyTotal hysterectomy
2021
Molecular Diagnosis
Weisman P, Wei J, Hui P. Molecular Diagnosis. Practical Anatomic Pathology 2021, 417-431. DOI: 10.1007/978-3-030-68608-6_16.Peer-Reviewed Original ResearchGynecologic pathologyMolecular diagnostic techniquesGynecologic tumorsCell tumorsTherapeutic implicationsOvarian sex cord-stromal tumorsHigh-grade endometrial stromal sarcomaSertoli-Leydig cell tumorSex cord-stromal tumorsJuvenile granulosa cell tumorMolecular diagnostic findingsSpindle cell leiomyosarcomaEndometrial stromal sarcomaGranulosa cell tumorsGestational trophoblastic diseaseLow mitotic ratePeutz-Jeghers syndromeDiagnostic techniquesFibrosarcoma-like tumorsStromal sarcomaOvarian neoplasiaSporadic settingHistological featuresTrophoblastic diseaseDiagnostic findings
2018
FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors
Buza N, Wong S, Hui P. FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors. International Journal Of Gynecological Pathology 2018, 37: 305-315. PMID: 28700438, DOI: 10.1097/pgp.0000000000000426.Peer-Reviewed Original ResearchConceptsSex cord-stromal tumorsAdult granulosa cell tumorGranulosa cell tumorsOvarian sex cord-stromal tumorsCell tumorsReticulin patternFOXL2 mutationStaining patternSertoli-Leydig cell tumorFOXL2 mutation statusAbundant pale cytoplasmSingle institutional cohortThird of casesWild-type tumorsFOXL2 mutation analysisNegative tumorsPositive tumorsTumor sizeReticulin stainingType tumorsPale cytoplasmNuclear atypiaMutation statusPositive casesTumors
2010
Nonepithelial Tumor of Ovary
Chhieng D, Hui P. Nonepithelial Tumor of Ovary. Current Clinical Pathology 2010, 173-191. DOI: 10.1007/978-1-60761-164-6_11.Peer-Reviewed Original Research