2024
Microbe Profile: Bacteriophage ϕ6: a model for segmented RNA viruses and the evolutionary consequences of viral ‘sex’
Turner P, Chao L. Microbe Profile: Bacteriophage ϕ6: a model for segmented RNA viruses and the evolutionary consequences of viral ‘sex’. Microbiology 2024, 170: 001467. PMID: 39046321, PMCID: PMC11316545, DOI: 10.1099/mic.0.001467.Peer-Reviewed Original ResearchMeSH KeywordsBacteriophage phi 6Evolution, MolecularHost-Pathogen InteractionsMutationRNA VirusesVirus ReplicationConceptsEukaryotic virusesHost-pathogen interactionsEvolution of sexDsRNA virusesEvolutionary consequencesSegment reassortmentBacterial virusesRNA virusesRate of adaptationMutation ratePhenotypic complexityMutation loadLipid envelopeBacteriophageReassortmentRNAMutationsVirusMolecular modelingDsRNAExperimental systemGeneticsTraitsHostReplication
2015
Rate of novel host invasion affects adaptability of evolving RNA virus lineages
Morley VJ, Mendiola SY, Turner PE. Rate of novel host invasion affects adaptability of evolving RNA virus lineages. Proceedings Of The Royal Society B 2015, 282: 20150801. PMID: 26246544, PMCID: PMC4632612, DOI: 10.1098/rspb.2015.0801.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, BiologicalBiological EvolutionEnvironmentHost-Pathogen InteractionsSindbis VirusConceptsNovel hostHost cell typesHost invasionCell typesVirus lineagesVirus populationsGenomic outcomesEnvironmental turnoverTissue culture environmentAbility of virusesHost typeRNA virusesConsensus sequencingInfluences adaptationLineagesGradual invasionHostHistorical contingencyMolecular substitutionDifferent genotypesAdaptive changesInvasionRapid shiftVirusSequencing
2008
Evolutionary Genomics of Host Adaptation in Vesicular Stomatitis Virus
Remold SK, Rambaut A, Turner PE. Evolutionary Genomics of Host Adaptation in Vesicular Stomatitis Virus. Molecular Biology And Evolution 2008, 25: 1138-1147. PMID: 18353798, DOI: 10.1093/molbev/msn059.Peer-Reviewed Original ResearchConceptsGenetic architectureComplex traitsHigher fitnessVirus populationsVesicular stomatitis virus populationsParallel phenotypic changesSimilar selection pressuresRNA virus populationsHigh mutation rateEvolutionary genomicsGenome evolutionHost useComplete consensus sequenceTrue pleiotropyHost adaptationAllele substitutionGenomic changesSelection pressureVesicular stomatitis virusConsensus sequenceMutation rateEcological historyPhenotypic changesRNA virusesHeLa cells