2020
Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma
Bilecz A, Stockhammer P, Theegarten D, Kern I, Jakopovic M, Samarzija M, Klikovits T, Hoda MA, Döme B, Oberndorfer F, Muellauer L, Fillinger J, Kovács I, Pirker C, Schuler M, Plönes T, Aigner C, Klepetko W, Berger W, Brcic L, Laszlo V, Hegedus B. Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma. Histopathology 2020, 77: 55-66. PMID: 32170970, DOI: 10.1111/his.14105.Peer-Reviewed Original ResearchConceptsMalignant pleural mesotheliomaEpithelioid malignant pleural mesotheliomaOverall survivalHistological subtypesPleural mesotheliomaIntensive multimodal treatment approachesEpithelioid pleural mesotheliomaIndependent prognostic factorShorter overall survivalHigh nuclear gradeMultimodal treatment approachCancer Genome Atlas (TCGA) databaseNuclear grading systemLonger OSPrognostic factorsPrognostic impactPrognostic roleRare malignancyDismal prognosisTrabecular variantMultimodal treatmentPrognostic significancePatient cohortHistopathologic parametersMultimodal therapy
2019
Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters
Viehof J, Livingstone E, Loscha E, Stockhammer P, Bankfalvi A, Plönes T, Mardanzai K, Zimmer L, Sucker A, Schadendorf D, Hegedüs B, Aigner C. Prognostic factors for pulmonary metastasectomy in malignant melanoma: size matters. European Journal Of Cardio-Thoracic Surgery 2019, 56: 1104-1109. PMID: 31321422, DOI: 10.1093/ejcts/ezz211.Peer-Reviewed Original ResearchConceptsPulmonary metastasectomyOverall survival rateNovel treatment optionsPrognostic factorsSurvival rateFemale patientsTreatment optionsMalignant melanomaSurvival timeExcellent overall survival ratesSignificant independent prognostic factorImproved long-term outcomesShorter overall survival timeComplete pulmonary metastasectomyPreoperative systemic therapyIndependent prognostic factorNumber of metastasesPrognosis of patientsSelection of patientsOverall survival timeLong-term outcomesMedian survival timeImpact of ageBilateral metastasesMedian follow