2009
Conceptualizing Autism: The Role for Emergence
Lombroso P, Ogren M, Anderson G. Conceptualizing Autism: The Role for Emergence. Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 688-691. PMID: 19542823, DOI: 10.1097/chi.0b013e3181a5e3d5.Peer-Reviewed Original ResearchAdolescentAptitudeAutistic DisorderBrainChildComorbidityDiseases in TwinsEpistasis, GeneticGenetic Predisposition to DiseaseGenotypeHumansIntellectual DisabilityMultifactorial InheritancePhenotypeReceptor, Serotonin, 5-HT2AReflex, AbnormalSeizuresSelf-Injurious BehaviorSerotoninStereotyped BehaviorSystems TheoryYoung Adult
2001
Genetics of Childhood Disorders: XXXI. Autoimmune Disorders, Part 4: Is Sydenham Chorea an Autoimmune Disorder?
LOISELLE C, SINGER H, Lombroso P. Genetics of Childhood Disorders: XXXI. Autoimmune Disorders, Part 4: Is Sydenham Chorea an Autoimmune Disorder? Journal Of The American Academy Of Child & Adolescent Psychiatry 2001, 40: 1234-1236. PMID: 11589538, DOI: 10.1097/00004583-200110000-00019.Peer-Reviewed Original ResearchAntibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders
Morshed S, Parveen S, Leckman J, Mercadante M, Kiss M, Miguel E, Arman A, Yazgan Y, Fujii T, Paul S, Peterson B, Zhang H, King R, Scahill L, Lombroso P. Antibodies against neural, nuclear, cytoskeletal, and streptococcal epitopes in children and adults with Tourette’s syndrome, Sydenham’s chorea, and autoimmune disorders. Biological Psychiatry 2001, 50: 566-577. PMID: 11690591, DOI: 10.1016/s0006-3223(01)01096-4.Peer-Reviewed Original ResearchConceptsTotal antinuclear antibodiesAntinuclear antibodiesAutoimmune disordersTourette syndromeAnticytoskeletal antibodiesAntineural antibodiesStreptococcal infectionT patientsTS patientsBeta-hemolytic streptococcal infectionPrior streptococcal infectionHemolytic streptococcal infectionAntistreptolysin O titerIndirect immunofluorescent assayLevels of immunoreactivityWestern blot techniqueMean rankClinical characteristicsSydenham's choreaO titerPatient groupSC patientsIgG antibodiesIgG classNormal controlsGenetics of Central Nervous System Developmental Disorders
Naegele J, Lombroso P. Genetics of Central Nervous System Developmental Disorders. Child And Adolescent Psychiatric Clinics Of North America 2001, 10: 225-239. PMID: 11351796, DOI: 10.1016/s1056-4993(18)30055-5.Peer-Reviewed Original Research
1999
Genetics of Childhood Disorders: IV. Linkage Analysis
Lombroso P, PAULS D. Genetics of Childhood Disorders: IV. Linkage Analysis. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 932-934. PMID: 10405513, DOI: 10.1097/00004583-199907000-00025.Peer-Reviewed Original Research
1995
Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report
LOMBROSO P, SCAHILL L, KING R, LYNCH K, CHAPPELL P, PETERSON B, McDOUGLE C, LECKMAN J. Risperidone Treatment of Children and Adolescents with Chronic Tic Disorders: A Preliminary Report. Journal Of The American Academy Of Child & Adolescent Psychiatry 1995, 34: 1147-1152. PMID: 7559308, DOI: 10.1097/00004583-199509000-00011.Peer-Reviewed Original ResearchConceptsChronic tic disorderTic disordersObsessive-compulsive disorderChronic motor tic disorderYale Global Tic Severity ScaleDopamine-blocking propertiesOpen-label trialFrequent side effectsEfficacy of risperidoneMotor tic disorderShort-term safetyTic Severity ScaleComorbid obsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleClinical responseRisperidone treatmentMean ageTic scoreSeverity ScaleSide effectsTourette syndromeComorbid diagnosesTic frequencyWeight gain
1991
Emergence of Self-Destructive Phenomena in Children and Adolescents during Fluoxetine Treatment
KING R, RIDDLE M, CHAPPELL P, HARDIN M, ANDERSON G, LOMBROSO P, SCAHILL L. Emergence of Self-Destructive Phenomena in Children and Adolescents during Fluoxetine Treatment. Journal Of The American Academy Of Child & Adolescent Psychiatry 1991, 30: 179-186. PMID: 2016219, DOI: 10.1097/00004583-199103000-00003.Peer-Reviewed Original ResearchConceptsFluoxetine treatmentObsessive-compulsive disorderUniversity Clinical Research CenterClinical Research CenterMajor risk factorDrug-induced activationPrior suicidal ideationYounger patientsRisk factorsRegulation of aggressionPatientsSuicidal ideationSelf-destructive behaviorFluoxetineAge 10Apparent associationVulnerable individualsDisordersTreatmentIdeationDe novoHospitalizationSymptoms