Limited Efficacy of Ketoconazole in Treatment-Refractory Major Depression
Malison R, Anand A, Pelton G, Kirwin P, Carpenter L, McDougle C, Heninger G, Price L. Limited Efficacy of Ketoconazole in Treatment-Refractory Major Depression. Journal Of Clinical Psychopharmacology 1999, 19: 466-470. PMID: 10505589, DOI: 10.1097/00004714-199910000-00011.Peer-Reviewed Original ResearchConceptsTreatment-refractory major depressionClinical Global Impression ScaleBeck Depression InventoryMajor depressionLimited efficacyTreatment-refractory major depressive disorderPlacebo-controlled trialGlobal Impression ScaleEfficacy of ketoconazoleHamilton Rating ScaleMajor depressive disorderAssessment of moodCGI scoresImpression ScaleDepressive disorderPatientsDepression InventoryRating ScaleKetoconazolePlaceboDepressionEfficacySignificant reductionTrials