2023
Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application
Heerdt P, Martin-Flores M, Oakland H, Joseph P, Singh I. Integrating Right Ventricular Pressure Waveform Analysis With Two-Point Volume Measurement for Quantification of Systolic and Diastolic Function: Experimental Validation and Clinical Application. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 1929-1937. PMID: 37422337, PMCID: PMC10529383, DOI: 10.1053/j.jvca.2023.06.011.Peer-Reviewed Original ResearchConceptsRight heart catheterizationHeart catheterizationDiastolic functionRV volumesBeat measuresDiagnostic right heart catheterizationReference standardRight ventricular contractilityEnd-diastolic pressurePressure waveform analysisEnd-systolic elastancePotential clinical utilityClinical applicationRV volume measurementsVolume measurementsRV contractilityRV systolicVentricular contractilityRV pressureBland-Altman analysisClinical utilityAnesthetized swineNitric oxideExperimental modelContractility
2009
Case report: paradoxical ventricular septal motion in the setting of primary right ventricular myocardial failure
Maslow A, Schwartz C, Mahmood F, Singh A, Heerdt PM. Case report: paradoxical ventricular septal motion in the setting of primary right ventricular myocardial failure. Journal Canadien D'anesthésie 2009, 56: 510-517. PMID: 19475470, DOI: 10.1007/s12630-009-9108-8.Peer-Reviewed Original ResearchConceptsRV myocardial tissueRV ejectionSystemic hypotensionSeptal motionParadoxical ventricular septal motionMyocardial tissueRV fractional areaVentricular septal motionEnd-organ dysfunctionRight heart failureRight ventricular failureMitral valve replacementVentricular systolic functionEarly postoperative periodSystemic organ failureSystemic organ functionSystolic septal motionMultiple inotropesVasopressor administrationVentricular failureEchocardiographic evaluationHemodynamic instabilityInotropic medicationsPostoperative periodSystolic function
1996
Nitric oxide synthesis inhibition and right ventricular systolic function in swine
Heerdt P, Pleimann B. Nitric oxide synthesis inhibition and right ventricular systolic function in swine. Journal Of Cardiothoracic And Vascular Anesthesia 1996, 10: 909-914. PMID: 8969400, DOI: 10.1016/s1053-0770(96)80055-3.Peer-Reviewed Original ResearchConceptsRV end-diastolic pressureTotal arterial resistanceL-NAMERV afterloadPA elastanceArterial resistanceNitric oxide synthesis inhibitor NG-nitroNitric oxide synthesis inhibitionRight ventricular systolic functionL-arginine methyl esterMean PA pressurePulmonary arterial pressureRight ventricular contractilityVentricular systolic functionEnd-diastolic pressureIndex of contractilityPeak ejection rateUniversity animal laboratoryLarge pulmonary vesselsIndex of RVRV powerArterial pressureSystolic functionNG-nitroResistance vessels