Disparity of isoflurane effects on left and right ventricular afterload and hydraulic power generation in swine.
Heerdt P, Gandhi C, Dickstein M. Disparity of isoflurane effects on left and right ventricular afterload and hydraulic power generation in swine. Anesthesia & Analgesia 1998, 87: 511-21. PMID: 9728819, DOI: 10.1097/00000539-199809000-00002.Peer-Reviewed Original ResearchConceptsPreload recruitable stroke work slopeDose-related decreaseRight ventricleLeft ventricleISO groupMinimum alveolar anesthetic concentration (MAC) isofluraneIso animalsPulmonary arterial blood flowIsoflurane-induced alterationsRight ventricular afterloadTotal arterial resistanceDose-related effectsEffects of isofluranePeak systolic pressureAutonomic nervous activityArterial blood flowGroups of swineRegional segment lengthVolatile Anesthetic EffectsEjection of bloodBiventricular contractilityRV contractilityVascular effectsVentricular afterloadSystolic pressure