2012
Transcriptomic analysis reveals atrial KCNE1 down‐regulation following lung lobectomy
Heerdt PM, Kant R, Hu Z, Kanda VA, Christini DJ, Malhotra JK, Abbott GW. Transcriptomic analysis reveals atrial KCNE1 down‐regulation following lung lobectomy. Journal Of Molecular And Cellular Cardiology 2012, 53: 350-353. PMID: 22641150, PMCID: PMC3418454, DOI: 10.1016/j.yjmcc.2012.05.010.Peer-Reviewed Original ResearchConceptsEffective refractory periodLone atrial fibrillationAtrial fibrillationPostoperative AFLung lobectomyLeft atriumNew-onset postoperative atrial fibrillationMean pulmonary artery pressurePostoperative atrial fibrillationPulmonary vascular resistanceUpper lung lobectomyPulmonary artery pressureTelemetric ECGArtery pressureVascular resistanceMajor surgeryHemodynamic variablesFunction polymorphismLA tissuesRefractory periodWestern blottingProtein levelsGene sequence variantsMolecular changesLobectomy
2010
Pharmacodynamics and Cardiopulmonary Side Effects of CW002, a Cysteine-reversible Neuromuscular Blocking Drug in Dogs
Heerdt PM, Malhotra JK, Pan BY, Sunaga H, Savarese JJ. Pharmacodynamics and Cardiopulmonary Side Effects of CW002, a Cysteine-reversible Neuromuscular Blocking Drug in Dogs. Anesthesiology 2010, 112: 910-916. PMID: 20234311, DOI: 10.1097/aln.0b013e3181d31f71.Peer-Reviewed Original ResearchConceptsX ED95Neuromuscular blocking drugsCardiopulmonary side effectsVascular resistanceArterial pressureBlocking drugsCardiac outputHistamine releaseSide effectsMean pulmonary artery pressurePulmonary artery pressurePulmonary vascular resistanceSystemic vascular resistanceMean arterial pressurePulmonary arterial pressureArtery pressureHemodynamic effectsPulmonary complianceVentricular contractilityInspiratory pressureNeuromuscular blockadeVentricular pressureED95Large dosesCW002
1990
Prostaglandin E1 and intrapulmonary shunt in cardiac surgical patients with pulmonary hypertension
Heerdt P, Weiss C. Prostaglandin E1 and intrapulmonary shunt in cardiac surgical patients with pulmonary hypertension. The Annals Of Thoracic Surgery 1990, 49: 463-465. PMID: 2106846, DOI: 10.1016/0003-4975(90)90257-7.Peer-Reviewed Original ResearchConceptsPulmonary vascular resistancePulmonary capillary wedge pressureCapillary wedge pressurePulmonary arterial pressureSystemic vascular resistanceVascular resistanceIntrapulmonary shuntPulmonary hypertensionProstaglandin E1Wedge pressureArterial pressureSurgical patientsCardiac outputElevated pulmonary vascular resistanceMean pulmonary arterial pressureAdult respiratory distress syndromeMixed venous oxygen tensionPulmonary vascular responseCardiac surgical patientsRight atrial pressureRespiratory distress syndromeProstaglandin E1 infusionPulmonary arterial catheterRadial arterial cannulaVenous oxygen tension