2023
Pulmonary artery wave intensity analysis in a pig model of lung resection
KEAST T, GLASS A, MCCALL P, SHELLEY B, HEERDT P. Pulmonary artery wave intensity analysis in a pig model of lung resection. Journal Of Cardiothoracic And Vascular Anesthesia 2023, 37: 9-10. DOI: 10.1053/j.jvca.2023.08.023.Peer-Reviewed Original ResearchForward compression waveBackward compression waveWave intensity analysisControl subjectsLung resectionPulmonary arteryPig modelSystolic timeCardiovascular MRIInvasive haemodynamic dataPulmonary artery pressureRight ventricular functionProximal pulmonary arteriesMain pulmonary arteryPost-operative patientsRight ventricular contractionWave reflection indicesMann-Whitney testIncreased afterloadLabChart softwareArtery pressureHaemodynamic effectsRV functionUpper lobectomyVentricular function
2008
Activation of brain protein phosphatase‐1I following cardiac arrest and resuscitation involving an interaction with 14‐3‐3γ
Platholi J, Heerdt PM, Tung H, Hemmings HC. Activation of brain protein phosphatase‐1I following cardiac arrest and resuscitation involving an interaction with 14‐3‐3γ. Journal Of Neurochemistry 2008, 105: 2029-2038. PMID: 18284617, PMCID: PMC3872065, DOI: 10.1111/j.1471-4159.2008.05300.x.Peer-Reviewed Original ResearchConceptsGlobal cerebral ischemiaCerebral ischemiaCardiac arrestTransient global cerebral ischemiaTransient cerebral ischemiaPotential therapeutic targetRelevant pig modelIschemic brainNeuroprotective mechanismsControl brainsInhibitory modulatorTherapeutic targetPig modelIschemiaPig brainBrain proteinsMechanism-based approachBrainProtein betaResuscitationEnergy metabolismCritical regulatorArrestVivoActivation