Differential regulation of protein phosphatase-1I by neurabin
Bullock SA, Platholi J, Gjyrezi A, Heerdt PM, Tung HY, Hemmings HC. Differential regulation of protein phosphatase-1I by neurabin. Biochemical And Biophysical Research Communications 2007, 358: 140-144. PMID: 17467665, PMCID: PMC1989152, DOI: 10.1016/j.bbrc.2007.04.076.Peer-Reviewed Original ResearchConceptsProtein phosphatase 1Phosphatase 1Protein phosphatase 1IProtein phosphataseActivation domainMultimeric complexesRegulatory subunitCatalytic subunitSubcellular localizationProtein kinaseSubstrate specificityRegulatory proteinsUnidentified proteinsNeurabinDifferential regulationNovel mechanismProteinSubunitsRegulationMajor formDistinct formsDependent formKinaseActinActivatorProtein phosphatase‐1I activation in brain following cardiac arrest and resuscitation
Platholi J, Heerdt P, Tung H, Hemmings H. Protein phosphatase‐1I activation in brain following cardiac arrest and resuscitation. The FASEB Journal 2007, 21: a618-a619. DOI: 10.1096/fasebj.21.5.a618-d.Peer-Reviewed Original ResearchProtein phosphatase 1Cerebral ischemiaCellular energy metabolismPig brainApoptotic cell deathTransient global cerebral ischemiaPhosphatase 1Protein regulatorsGlobal cerebral ischemiaPP-1Major proteinsInhibitor 2Cell deathSubunit compositionEnergy metabolismIntact animal modelIonic balanceCardiac arrestAnimal modelsProtective mechanismBrainIschemiaDeathDependent formRegulator