2002
Increasing drug users’ adherence to HIV treatment: results of a peer-driven intervention feasibility study
Broadhead RS, Heckathorn DD, Altice FL, van Hulst Y, Carbone M, Friedland GH, O’Connor P, Selwyn PA. Increasing drug users’ adherence to HIV treatment: results of a peer-driven intervention feasibility study. Social Science & Medicine 2002, 55: 235-246. PMID: 12144138, DOI: 10.1016/s0277-9536(01)00167-8.Peer-Reviewed Original ResearchConceptsActive drug usersDrug users' adherenceDrug usersDrug treatmentMedical carePrimary careIntervention feasibility studySocial support structuresHealth advocatesUser adherenceTreatment program staffPeer-driven interventionHIV diseaseHIV infectionPatient adherenceSix-month studyHIV treatmentPhysician referralClinical appointmentsHIV therapeuticsCarePositive behavioral changesAdherencePeer pressureTreatment
2000
HIV post-exposure therapy for drug users in treatment
O'Connor P. HIV post-exposure therapy for drug users in treatment. Journal Of Substance Use And Addiction Treatment 2000, 18: 17-21. PMID: 10636602, DOI: 10.1016/s0740-5472(99)00015-x.Peer-Reviewed Original ResearchConceptsPost-exposure therapyMethadone maintenance programDrug usersOccupational exposurePrimary care providersCross-sectional evaluationHIV prevention messagesGroups of providersNonoccupational exposureProvider staffNeedle stickDrug treatmentCare providersFocus groupsPrevention messagesTreatment programProgram providersTreatment staffFurther studiesHIVFuture riskTherapyTreatmentCase vignettesExposure
1999
Tuberculosis chemoprophylaxis using a liquid isoniazid‐methadone admixture for drug users in methadone maintenance
O'Connor PG, Shi JM, Henry S, Durante AJ, Friedman L, Selwyn PA. Tuberculosis chemoprophylaxis using a liquid isoniazid‐methadone admixture for drug users in methadone maintenance. Addiction 1999, 94: 1071-1075. PMID: 10707445, DOI: 10.1046/j.1360-0443.1999.947107112.x.Peer-Reviewed Original ResearchConceptsMethadone maintenanceTuberculosis chemoprophylaxisDrug usersMedian durationDaily doseOpioid-dependent drug usersProspective cohort studyMethadone maintenance programDrug treatment programsCompleting therapyINH chemoprophylaxisINH prophylaxisCohort studyEligible subjectsINH therapyCommon reasonChemoprophylaxisTherapyVitamin B6Treatment programMethadoneIsoniazidSubjectsINHDuration
1998
Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment
Durante AJ, Selwyn PA, O'Connor PG. Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment. Addiction 1998, 93: 1393-1401. PMID: 9926545, DOI: 10.1046/j.1360-0443.1998.939139310.x.Peer-Reviewed Original ResearchConceptsMycobacterium tuberculosis infectionTB knowledgeTuberculosis infectionDrug treatment programsRisk factorsDrug usersPositive TB skin testsTreatment programTB skin testTB risk factorsM. tuberculosis infectionTuberculin skin testingLow TB incidenceNeedles/syringesNon-white raceIncidence of infectionDrug treatment facilitiesPrevalence of infectionSubstance abuse treatmentSubsample of clientsPreventive therapyTB controlSkin testingTB incidenceInfected subjects
1997
Treatment of Early AIDS Dementia in Intravenous Drug Users: High Versus Low Dose Peptide T
Kosten T, Rosen M, McMahon T, Bridge T, O'malley S, Pearsall R, O'connor P. Treatment of Early AIDS Dementia in Intravenous Drug Users: High Versus Low Dose Peptide T. The American Journal Of Drug And Alcohol Abuse 1997, 23: 543-553. PMID: 9366972, DOI: 10.3109/00952999709016894.Peer-Reviewed Original Research
1996
Substance Abuse and HIV/AIDS in Poland: Opportunities for Educational Exchange1
O'Connor P, Williams A. Substance Abuse and HIV/AIDS in Poland: Opportunities for Educational Exchange1. Substance Use & Addiction Journal 1996, 17: 101-109. DOI: 10.1080/08897079609444734.Peer-Reviewed Original ResearchInjection drug usersMethadone maintenance treatmentEpidemic of HIVSubstance abuse treatment systemLong-term residential treatmentEffective substance abuse treatmentClinical treatment approachesHIV/AIDSSubstance abuse treatmentHIV infectionMaintenance treatmentClean needlesHIV riskTreatment approachesDrug usersMedical careCocaine useMedical UniversityAbuse treatmentSubstance abuseResidential treatmentCareTreatmentAddiction problemsOpioids
1995
Models of Medical Care for HIV-infected Drug Users
Samet J, Stein M, O'Connor P. Models of Medical Care for HIV-infected Drug Users. Substance Use & Addiction Journal 1995, 16: 131-139. DOI: 10.1080/08897079509444716.Peer-Reviewed Original ResearchPrimary care-based ambulatory opioid detoxification
O’Connor P, Waugh M, Carroll K, Rounsaville B, Diagkogiannis I, Schottenfeld R. Primary care-based ambulatory opioid detoxification. Journal Of General Internal Medicine 1995, 10: 255-260. PMID: 7616334, DOI: 10.1007/bf02599882.Peer-Reviewed Original ResearchConceptsInjection drug usersClonidine/naltrexoneOpioid detoxificationDrug treatmentProspective nonrandomized clinical trialMedical clinicsPrimary care medical clinicFirst heroin useOngoing drug treatmentNonrandomized clinical trialPrimary care providersWithdrawal symptom scoresSubstance abuse treatmentMuscle crampsSymptom scoresClinical trialsClonidineNurse practitionersCare providersDetoxified patientsHeroin useTreatment groupsNaltrexoneDrug usersMedical units
1994
HIV infection and cocaine use in methadone maintained and untreated intravenous drug users
Meandzija B, O'Connor P, Fitzgerald B, Rounsaville B, Kosten T. HIV infection and cocaine use in methadone maintained and untreated intravenous drug users. Drug And Alcohol Dependence 1994, 36: 109-113. PMID: 7851277, DOI: 10.1016/0376-8716(94)90092-2.Peer-Reviewed Original ResearchConceptsIntravenous drug usersMethadone maintenance treatmentMethadone maintenance programHIV infectionCocaine useMore cocaine useMaintenance treatmentRisk factorsDrug usersMethadone maintenance treatment groupHuman immunodeficiency virus (HIV) transmissionAfrican AmericansMaintenance treatment groupNon-infected subjectsInjection frequencyHIV-negativeHIV testingDrug injectionStratified analysisTreatment groupsTotal cocaineHIVRisk behaviorsGreater riskInfectionManagement of hospitalized intravenous drug users: Role of the internist
O'Connor P, Samet J, Stein M. Management of hospitalized intravenous drug users: Role of the internist. The American Journal Of Medicine 1994, 96: 551-558. PMID: 8017454, DOI: 10.1016/0002-9343(94)90096-5.Peer-Reviewed Original ResearchConceptsIntravenous drug usersDrug usersHIV statusHospital settingPatient's HIV statusCommon clinical dilemmaHospital discharge planningInpatient hospital settingSignificant clinical challengeCommon behavioral issuesSubstance use problemsDrug withdrawalDischarge planningClinical dilemmaClinical challengeMEDLINE searchMedical problemsInternistsUse problemsBehavioral issuesAppropriate knowledgeRelevant literatureManagementReviewEpidemiology
1992
Human immunodeficiency virus infection in intravenous drug users: A model for primary care
O'Connor P, Molde S, Henry S, Shockcor W, Schottenfeld R. Human immunodeficiency virus infection in intravenous drug users: A model for primary care. The American Journal Of Medicine 1992, 93: 382-386. PMID: 1415300, DOI: 10.1016/0002-9343(92)90166-9.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus infectionPrimary careTuberculosis prophylaxisSyphilis treatmentVirus infectionDrug treatmentDrug usersPneumocystis carinii pneumonia prophylaxisHepatitis B vaccinePrimary care clinicsPrimary care servicesT-cell testingEligible patientsPneumonia prophylaxisAntiretroviral therapyB vaccineChart reviewPneumococcal vaccineT helperHIV infectionInfluenza vaccineCare clinicsMethadone maintenancePeptide T Treatment of Cognitive Impairment in HIV‐Positive Intravenous Drug Users
Rosen M, Bridge T, O'Malley S, Pearsall H, Martini B, O'Connor P, Brett‐Smith H, Thomas H, Van Dyck C, Woods S, Kosten T. Peptide T Treatment of Cognitive Impairment in HIV‐Positive Intravenous Drug Users. American Journal On Addictions 1992, 1: 332-338. DOI: 10.1111/j.1521-0391.1992.tb00359.x.Peer-Reviewed Original ResearchHIV-positive intravenous drug usersDouble-blind crossover studyPeptide T treatmentHIV-positive patientsPeptide TOpen clinical trialIntravenous drug usersVasoactive intestinal peptideAIDS dementiaCrossover studyNeuropsychological improvementAZT treatmentIntestinal peptideClinical trialsDrug usersCognitive impairmentPatientsNeuropsychological functionCognitive functionT treatmentPlaceboThree timesWeeksPotential utilityTreatmentDIAGNOSIS AND TREATMENT OF SUBSTANCE USERS WITH HIV INFECTION
Selwyn P, O'Connor P. DIAGNOSIS AND TREATMENT OF SUBSTANCE USERS WITH HIV INFECTION. Primary Care Clinics In Office Practice 1992, 19: 119-156. PMID: 1594693, DOI: 10.1016/s0095-4543(21)00124-x.Peer-Reviewed Original ResearchConceptsHIV infectionDrug usersDrug-using patientsPrimary care cliniciansFavorable patient outcomesPrimary care providersPrimary care practitionersImportant clinical challengeSubstance use disordersDrug use problemsTreatment of substanceSubstance abuse problemsMedical complicationsPain managementCare cliniciansPatient outcomesComprehensive careDrug interactionsProvider awarenessClinical challengeDrug treatmentCare providersCare practitionersDrug useClinical staff