2001
Bcl-XL–Caspase-9 Interactions in the Developing Nervous System: Evidence for Multiple Death Pathways
Zaidi A, D'Sa-Eipper C, Brenner J, Kuida K, Zheng T, Flavell R, Rakic P, Roth K. Bcl-XL–Caspase-9 Interactions in the Developing Nervous System: Evidence for Multiple Death Pathways. Journal Of Neuroscience 2001, 21: 169-175. PMID: 11150333, PMCID: PMC6762421, DOI: 10.1523/jneurosci.21-01-00169.2001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBcl-2-Associated X ProteinBcl-X ProteinCaspase 3Caspase 9CaspasesCells, CulturedCytarabineGanglia, SpinalGenes, LethalHeterozygoteHomozygoteImmunohistochemistryIn Situ Nick-End LabelingLiverMiceMice, KnockoutNervous SystemNeuronsProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2TelencephalonTumor Suppressor Protein p53ConceptsGene family membersCaspase-9 deficiencyCaspase-9Telencephalic neural precursor cellsCell deathDouble homozygous mutantsCaspase family membersMultiple death pathwaysNormal nervous system developmentBcl-2Nervous system developmentBax-deficient neuronsNeuronal apoptosisTelencephalic neuronsDeficient embryosNeural precursor cellsDeath pathwaysFamily membersHomozygous mutantsApoptotic pathwayObligate pathwayBcl-xLApoptosis inducersDeficient neuronsTargeted disruption
1999
Illusive transience of parvalbumin expression duringembryonic development of the primate spinal cord
Knyihár‐csillik E, Rakic P, Csillik B. Illusive transience of parvalbumin expression duringembryonic development of the primate spinal cord. International Journal Of Developmental Neuroscience 1999, 17: 79-97. PMID: 10221668, DOI: 10.1016/s0736-5748(98)00090-2.Peer-Reviewed Original ResearchConceptsNerve cellsSpinal cordLarge dorsal root ganglion cellsDorsal root ganglion cellsYoung adult macaque monkeysPrimate spinal cordUpper dorsal hornDorsal root axonsPrimary sensory neuronsSpinal reflex pathwaysElectron microscopic immunohistochemical techniquesAdult macaque monkeysParvalbumin-positive terminalsLong axonal processesDorsal hornMonkey fetusesDorsal columnsReflex pathwaysGanglion cellsClarke's nucleusAxon terminalsIntercellular networkMotoneuron poolSensory neuronsSynaptic terminals
1997
Dorsal root origin of axonal growth cones: regenerative synapto-neogenesis in the upper spinal dorsal horn of primates.
Knyihár-Csillik E, Seres L, Rakic P, Csillik B. Dorsal root origin of axonal growth cones: regenerative synapto-neogenesis in the upper spinal dorsal horn of primates. Ideggyógyászati Szemle 1997, 5: 481-8. PMID: 9591285.Peer-Reviewed Original Research
1987
Transganglionic degenerative atrophy in the substantia gelatinosa of the spinal cord after peripheral nerve transection in rhesus monkeys
Knyihár-Csillik E, Rakic P, Csillik B. Transganglionic degenerative atrophy in the substantia gelatinosa of the spinal cord after peripheral nerve transection in rhesus monkeys. Cell And Tissue Research 1987, 247: 599-604. PMID: 3568105, DOI: 10.1007/bf00215754.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAtrophyGanglia, SpinalMacaca mulattaMicroscopy, ElectronNerve DegenerationSciatic NerveSpinal CordSubstantia GelatinosaConceptsTransganglionic degenerative atrophyNerve transectionSubstantia gelatinosaDegenerative atrophySpinal cordUpper dorsal hornPeripheral nerve injurySciatic nerve transectionPeripheral nerve transectionDiverse cellular changesDorsal hornNerve injuryDorsal rootsWallerian degenerationNociceptive systemGlial elementsSchwann cellsAdult rhesusRhesus monkeysCellular changesSynaptic vesiclesAtrophyTransectionCordGelatinosa
1982
Ultrastructure of normal and degenerating glomerular terminals of dorsal root axons in the substantia gelatinosa of the rhesus monkey
Knyihar‐Csillik E, Csillik B, Rakic P. Ultrastructure of normal and degenerating glomerular terminals of dorsal root axons in the substantia gelatinosa of the rhesus monkey. The Journal Of Comparative Neurology 1982, 210: 357-375. PMID: 7142447, DOI: 10.1002/cne.902100404.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAxonsFemaleGanglia, SpinalMacaca mulattaMaleMicroscopy, ElectronNerve DegenerationSpinal CordSynaptic VesiclesConceptsPrimary sensory terminalsDorsal root axonsLamina IIClear synaptic vesiclesSynaptic vesiclesSensory terminalsRhesus monkeysDorsal root transectionDorsal root fibersEmpty synaptic vesiclesAdult rhesus monkeysSynaptic vesicle populationDense-core vesiclesDeep collateralsDorsal hornRoot transectionSubstantia gelatinosaDorsal rootsPrimary afferentsGlomerular terminalsSpinal cordAxon terminalsGlial cellsPosterior hornDegeneration patternsPeriterminal synaptology of dorsal root glomerular terminals in the substantia gelatinosa of the spinal cord in the rhesus monkey
Knyigar‐Csillik E, Csillik B, Rakic P. Periterminal synaptology of dorsal root glomerular terminals in the substantia gelatinosa of the spinal cord in the rhesus monkey. The Journal Of Comparative Neurology 1982, 210: 376-399. PMID: 7142448, DOI: 10.1002/cne.902100405.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDendritesFemaleGanglia, SpinalMacaca mulattaMaleModels, NeurologicalSpinal CordSynapsesConceptsSubstantia gelatinosa cellsPresynaptic dendritesSubstantia gelatinosaGlomerular terminalsSpinal cordF-boutonsGlomerular complexRhesus monkeysPrimate central nervous systemPrimary afferent impulsesPrimary sensory terminalsCentral nervous systemDorsal root terminalsAdult rhesus monkeysNociceptive informationPostsynaptic modulationPrimary afferentsAdjacent glomeruliPostsynaptic dendritesSynaptic organization