2000
From Spontaneous to Induced Neurological Mutations: A Personal Witness of the Ascent of the Mouse Model
Rakic P. From Spontaneous to Induced Neurological Mutations: A Personal Witness of the Ascent of the Mouse Model. Results And Problems In Cell Differentiation 2000, 30: 1-19. PMID: 10857183, DOI: 10.1007/978-3-540-48002-0_1.Peer-Reviewed Original ResearchConceptsEssential model systemMosaic animalsLarge brain sizeSmall invertebratesGenome sequenceMolecular geneticsInduced mutationsVersatile animal modelArea of neurobiologyNormal developmentNeurological mutationDevelopmental neurobiologyBrain sizeModel systemMutationsMouse modelCongenital malformationsAnimal modelsNervous systemHuman nervous systemExperimental neuropathologyInvertebratesNonhuman primatesMammalsGenetics
1973
Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice
Rakic P, Sidman R. Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice. The Journal Of Comparative Neurology 1973, 152: 133-161. PMID: 4761656, DOI: 10.1002/cne.901520203.Peer-Reviewed Original ResearchConceptsGranule cellsExternal granular layerGolgi type II neuronsPurkinje cellsHeterozygous weaver miceType II neuronsMossy fiber terminalsWeaver mutant micePurkinje cell dendritesGranular layerExternal granule cellsIntrinsic axonsLocal cellular milieuSynaptic contactsForm synapsesEarly recognitionAxonal contactCell dendritesPostsynaptic elementsBergmann glial fibersMembrane thickeningMossy fibersDendritic spinesFiber terminalsMolecular layerSequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice
Rakic P, Sidman R. Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice. The Journal Of Comparative Neurology 1973, 152: 103-132. PMID: 4128371, DOI: 10.1002/cne.901520202.Peer-Reviewed Original Research