Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes
Bargieri D, Thiberge S, Tay C, Carey A, Rantz A, Hischen F, Lorthiois A, Straschil U, Singh P, Singh S, Triglia T, Tsuboi T, Cowman A, Chitnis C, Alano P, Baum J, Pradel G, Lavazec C, Ménard R. Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes. Cell Host & Microbe 2016, 20: 618-630. PMID: 27832590, PMCID: PMC5104695, DOI: 10.1016/j.chom.2016.10.015.Peer-Reviewed Original ResearchConceptsFamily proteinsGamete egressParasite motilityCell invasionErythrocyte invasionMembrane disruptionParasitophorous vacuole membraneMalaria parasite PlasmodiumBlood stage formsApicomplexan parasitesVacuole membraneExtracellular environmentParasite PlasmodiumActomyosin motorParasite transmissionTRAP proteinProteinCell egressStage formsInvasionEgressFalciparum parasitesParasitesIntegral roleMotility