Molecular mechanisms that mediate invasion and egress of malaria parasites from red blood cells
Alaganan A, Singh P, Chitnis C. Molecular mechanisms that mediate invasion and egress of malaria parasites from red blood cells. Current Opinion In Hematology 2017, 24: 208-214. PMID: 28306665, DOI: 10.1097/moh.0000000000000334.Peer-Reviewed Original ResearchConceptsMalaria parasitesMolecular mechanismsPerforin-like proteinComplex life cycleHost cell invasionDiverse host cellsCurrent understandingDevelopment of inhibitorsDifferent life cycle stagesFemale gametesTimely secretionKey effector moleculesRegulated mannerMolecular basisFemale gametocytesVesicular organellesMosquito midgutFemale anopheline mosquitoesProtein ligandsHost cellsLife cycle stagesCell invasionFunctional roleEffector moleculesParasite growth