BacCapSeq: a Platform for Diagnosis and Characterization of Bacterial Infections
Allicock O, Guo C, Uhlemann A, Whittier S, Chauhan L, Garcia J, Price A, Morse S, Mishra N, Briese T, Lipkin W. BacCapSeq: a Platform for Diagnosis and Characterization of Bacterial Infections. MBio 2018, 9: 10.1128/mbio.02007-18. PMID: 30352937, PMCID: PMC6199491, DOI: 10.1128/mbio.02007-18.Peer-Reviewed Original ResearchConceptsHigh-throughput sequencingVirulence Factor DatabaseComprehensive Antibiotic Resistance DatabaseBacterial infectionsResistance genesAntimicrobial resistance genesHealth care costsHuman pathogenic speciesUnbiased high-throughput sequencingAntimicrobial sensitivity profileCharacterization of bacteriaDifferential diagnosisReal-time PCRBlood samplesCare costsCenter databaseTotal readsInappropriate useBacterial readsCapture sequencingBacterial speciesAntimicrobial resistanceVirulence determinantsVirulence factorsFactor database