2022
Prophylactic Use of Antifibrinolytics During Pediatric Cardiac Surgery With Cardiopulmonary Bypass on Postoperative Bleeding and Transfusion: A Systematic Review and Meta-Analysis
Schertz K, Karam O, Demetres M, Mayadunna S, Faraoni D, Nellis ME. Prophylactic Use of Antifibrinolytics During Pediatric Cardiac Surgery With Cardiopulmonary Bypass on Postoperative Bleeding and Transfusion: A Systematic Review and Meta-Analysis. Pediatric Critical Care Medicine 2022, 23: e517-e529. PMID: 35997516, DOI: 10.1097/pcc.0000000000003049.Peer-Reviewed Original ResearchConceptsChest tube outputQuality of evidenceCardiopulmonary bypassTranexamic acidCardiac surgeryMean decreaseTube outputPlatelet requirementsPlatelet transfusionsML/P-valueMeta-AnalysisSystematic reviewStandardized data extraction toolBlood product requirementsPediatric cardiac surgeryPlasma requirementsPreferred Reporting ItemsData extraction toolWeb of SciencePostoperative bleedingCyanotic patientsPlasma transfusionBlood lossRBC transfusion
2020
Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational study
Biboulet P, Motais C, Pencole M, Karam O, Dangelser G, Smilevitch P, Maissiat G, Capdevila X, Bringuier S. Preoperative erythropoietin within a patient blood management program decreases both blood transfusion and postoperative anemia: a prospective observational study. Transfusion 2020, 60: 1732-1740. PMID: 32681743, DOI: 10.1111/trf.15900.Peer-Reviewed Original ResearchConceptsPatient blood management programBlood management programBlood transfusionPostoperative anemiaPreoperative erythropoietinObservational studyElective primary hipProspective observational studyMajor thromboembolicPreoperative hemoglobinCardiovascular eventsPreoperative treatmentTransfusion rateHospital dischargePostoperative infusionPostoperative periodIntraoperative administrationMajor complicationsTranexamic acidPrimary hipKnee arthroplastySingle hospitalTransfusionPatientsSpecific efficacy